Michael O Woods
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Explore the profile of Michael O Woods including associated specialties, affiliations and a list of published articles.
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84
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2802
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Recent Articles
11.
Aglago E, Kim A, Lin Y, Qu C, Evangelou M, Ren Y, et al.
Cancer Res
. 2023 May;
83(15):2572-2583.
PMID: 37249599
Significance: This gene-environment interaction analysis revealed a genetic locus in FMN1/GREM1 that interacts with body mass index in colorectal cancer risk, suggesting potential implications for precision prevention strategies.
12.
Thomas M, Su Y, Rosenthal E, Sakoda L, Schmit S, Timofeeva M, et al.
medRxiv
. 2023 Feb;
PMID: 36789420
Polygenic risk scores (PRS) have great potential to guide precision colorectal cancer (CRC) prevention by identifying those at higher risk to undertake targeted screening. However, current PRS using European ancestry...
13.
Ugai T, Haruki K, Harrison T, Cao Y, Qu C, Chan A, et al.
Am J Gastroenterol
. 2023 Jan;
118(4):712-726.
PMID: 36707929
Introduction: Early-onset colorectal cancer diagnosed before the age of 50 years has been increasing. Likely reflecting the pathogenic role of the intestinal microbiome, which gradually changes across the entire colorectal...
14.
Su Y, Sakoda L, Jeon J, Thomas M, Lin Y, Schneider J, et al.
Cancer Epidemiol Biomarkers Prev
. 2023 Jan;
32(3):353-362.
PMID: 36622766
Background: Polygenic risk scores (PRS) which summarize individuals' genetic risk profile may enhance targeted colorectal cancer screening. A critical step towards clinical implementation is rigorous external validations in large community-based...
15.
Carreras-Torres R, Kim A, Lin Y, Diez-Obrero V, Bien S, Qu C, et al.
Cancer Epidemiol Biomarkers Prev
. 2022 Dec;
32(3):315-328.
PMID: 36576985
Background: Tobacco smoking is an established risk factor for colorectal cancer. However, genetically defined population subgroups may have increased susceptibility to smoking-related effects on colorectal cancer. Methods: A genome-wide interaction...
16.
Lu Y, Zhao Y, Chang-Claude J, Gruber S, Gsur A, Offit K, et al.
Cancer Epidemiol Biomarkers Prev
. 2022 Dec;
32(2):281-286.
PMID: 36512731
Background: Mechanistic data indicate the benefit of short-chain fatty acids (SCFA) produced by gut microbial fermentation of fiber on colorectal cancer, but direct epidemiologic evidence is limited. A recent study...
17.
Murphy N, Newton C, Song M, Papadimitriou N, Hoffmeister M, Phipps A, et al.
J Natl Cancer Inst
. 2022 Nov;
115(2):165-173.
PMID: 36445035
Background: Obesity is an established risk factor for colorectal cancer (CRC), but the evidence for the association is inconsistent across molecular subtypes of the disease. Methods: We pooled data on...
18.
Haas C, Su Y, Petersen P, Wang X, Bien S, Lin Y, et al.
Sci Rep
. 2022 Nov;
12(1):18852.
PMID: 36344807
Observational studies have shown higher folate consumption to be associated with lower risk of colorectal cancer (CRC). Understanding whether and how genetic risk factors interact with folate could further elucidate...
19.
Tian Y, Kim A, Bien S, Lin Y, Qu C, Harrison T, et al.
J Natl Cancer Inst
. 2022 May;
114(8):1135-1148.
PMID: 35512400
Background: The use of menopausal hormone therapy (MHT) may interact with genetic variants to influence colorectal cancer (CRC) risk. Methods: We conducted a genome-wide, gene-environment interaction between single nucleotide polymorphisms...
20.
Jordahl K, Shcherbina A, Kim A, Su Y, Lin Y, Wang J, et al.
Cancer Epidemiol Biomarkers Prev
. 2022 Apr;
31(5):1077-1089.
PMID: 35438744
Background: Currently known associations between common genetic variants and colorectal cancer explain less than half of its heritability of 25%. As alcohol consumption has a J-shape association with colorectal cancer...