Michael Niepmann
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Explore the profile of Michael Niepmann including associated specialties, affiliations and a list of published articles.
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1621
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Recent Articles
1.
Niepmann M
Cancers (Basel)
. 2024 Jul;
16(13).
PMID: 39001354
Cancer cells metabolize a large fraction of glucose to lactate, even under a sufficient oxygen supply. This phenomenon-the "Warburg Effect"-is often regarded as not yet understood. Cancer cells change gene...
2.
Triebel S, Lamkiewicz K, Ontiveros N, Sweeney B, Stadler P, Petrov A, et al.
Sci Rep
. 2024 Jul;
14(1):15145.
PMID: 38956134
Hepatitis C virus (HCV) is a plus-stranded RNA virus that often chronically infects liver hepatocytes and causes liver cirrhosis and cancer. These viruses replicate their genomes employing error-prone replicases. Thereby,...
3.
Andreev D, Niepmann M, Shatsky I
Int J Mol Sci
. 2022 Dec;
23(24).
PMID: 36555135
The phenomenon of internal initiation of translation was discovered in 1988 on poliovirus mRNA. The prototypic -acting element in the 5' untranslated region (5'UTR) of poliovirus mRNA, which is able...
4.
Gerresheim G, Hess C, Shalamova L, Fricke M, Marz M, Andreev D, et al.
Int J Mol Sci
. 2020 Sep;
21(18).
PMID: 32971876
Hepatitis C virus (HCV) infects liver cells and often causes chronic infection, also leading to liver cirrhosis and cancer. In the cytoplasm, the viral structural and non-structural (NS) proteins are...
5.
Niepmann M, Gerresheim G
Int J Mol Sci
. 2020 Apr;
21(7).
PMID: 32230899
Translation of the hepatitis C virus (HCV) RNA genome is regulated by the internal ribosome entry site (IRES), located in the 5'-untranslated region (5'UTR) and part of the core protein...
6.
Gerresheim G, Roeb E, Michel A, Niepmann M
Cells
. 2019 Nov;
8(11).
PMID: 31717433
Hepatitis C Virus (HCV) mainly infects liver hepatocytes and replicates its single-stranded plus strand RNA genome exclusively in the cytoplasm. Viral proteins and RNA interfere with the host cell immune...
7.
Hu P, Wilhelm J, Gerresheim G, Shalamova L, Niepmann M
Viruses
. 2019 Jun;
11(6).
PMID: 31200545
Multiple host factors are known to play important roles in hepatitis C virus (HCV) replication, in immune responses induced by HCV infection, or in processes that facilitate virus escape from...
8.
Gerresheim G, Bathke J, Michel A, Andreev D, Shalamova L, Rossbach O, et al.
Int J Mol Sci
. 2019 Mar;
20(6).
PMID: 30875926
Background: Hepatitis C virus (HCV) infects human liver hepatocytes, often leading to liver cirrhosis and hepatocellular carcinoma (HCC). It is believed that chronic infection alters host gene expression and favors...
9.
Fricke M, Gerst R, Ibrahim B, Niepmann M, Marz M
Bioinformatics
. 2018 Aug;
35(4):579-583.
PMID: 30101307
Motivation: The protein-coding sequences of messenger RNAs are the linear template for translation of the gene sequence into protein. Nevertheless, the RNA can also form secondary structures by intramolecular base-pairing....
10.
Niepmann M, Shalamova L, Gerresheim G, Rossbach O
Front Microbiol
. 2018 Mar;
9:395.
PMID: 29593672
Hepatitis C virus (HCV) preferentially replicates in the human liver and frequently causes chronic infection, often leading to cirrhosis and liver cancer. HCV is an enveloped virus classified in the...