Michael Lekas
Overview
Explore the profile of Michael Lekas including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
136
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Recent Articles
1.
Qiang B, Lim S, Lekas M, Kuliszewski M, Wolff R, Osherov A, et al.
Can J Cardiol
. 2014 Sep;
30(11):1444-51.
PMID: 25249499
Background: Perlecan is a heparan sulfate proteoglycan (HSPG) constituent of the extracellular matrix with roles in cell growth, differentiation, and angiogenesis. The role of the HS side chains in regulating...
2.
Chen C, Lee S, Deshpande V, Lee G, Lekas M, Shepard K, et al.
Nat Nanotechnol
. 2013 Nov;
8(12):923-7.
PMID: 24240431
Oscillators, which produce continuous periodic signals from direct current power, are central to modern communications systems, with versatile applications including timing references and frequency modulators. However, conventional oscillators typically consist...
3.
Lekas M, Lekas P, Mei S, Deng Y, Dumont D, Stewart D
PLoS One
. 2012 Oct;
7(9):e43568.
PMID: 23049737
The angiopoietins (ANGPT) are ligands for the endothelial cell (EC) receptor tyrosine kinase, Tie2. Angpt-1 is a Tie2 agonist that promotes vascular maturation and stabilization, whereas Angpt-2 is a partial...
4.
Leong-Poi H, Kuliszewski M, Lekas M, Sibbald M, Teichert-Kuliszewska K, Klibanov A, et al.
Circ Res
. 2007 Jun;
101(3):295-303.
PMID: 17585071
Current methods of gene delivery for therapeutic angiogenesis are invasive, requiring either intraarterial or intramuscular administration. A noninvasive method of gene delivery has been developed using ultrasound-mediated destruction of intravenously...
5.
Lekas M, Lekas P, Latter D, Kutryk M, Stewart D
Curr Opin Cardiol
. 2006 Jun;
21(4):376-84.
PMID: 16755208
Purpose Of Review: Therapeutic angiogenesis and arteriogenesis represent an alternative treatment modality for patients with advanced ischaemic coronary or peripheral artery occlusive disease, who are unsuitable for standard revascularization procedures....
6.
Lekas M, Kutryk M, Latter D, Stewart D
Can J Cardiol
. 2004 Aug;
20 Suppl B:49B-57B.
PMID: 15309206
The demonstration that angiogenic growth factors stimulate new blood vessel growth and restore perfusion in animal models of myocardial and peripheral vascular ischemia has prompted the translation of therapeutic angiogenesis...