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Michael Knop

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Articles 99
Citations 3945
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Recent Articles
1.
Lazarewicz N, Le Dez G, Cerjani R, Runeshaw L, Meurer M, Knop M, et al.
Cell Rep Methods . 2024 Oct; 4(10):100880. PMID: 39437715
An accurate description of protein-protein interaction (PPI) networks is key to understanding the molecular mechanisms underlying cellular systems. Here, we constructed genome-wide libraries of yeast strains to systematically probe protein-protein...
2.
Sterr F, Bauernfeind L, Knop M, Rester C, Metzing S, Palm R
Nurs Crit Care . 2024 Aug; 29(6):1564-1579. PMID: 39155350
Background: Mechanical ventilation is a core intervention in critical care, but may also lead to negative consequences. Therefore, ventilator weaning is crucial for patient recovery. Numerous weaning interventions have been...
3.
Knop M, Mueller M, Kaiser S, Rester C
J Adv Nurs . 2024 Apr; 80(11):4346-4360. PMID: 38558440
Aim: This study seeks to review how the use of digital technologies in clinical nursing affects nurses' professional identity and the relations of power within clinical environments. Design: Literature review....
4.
Galka D, Ali T, Bast A, Niederleithinger M, Gerhardt E, Motosugi R, et al.
Aging Cell . 2024 Feb; 23(5):e14128. PMID: 38415292
Parkinson's disease (PD) is characterized by aggregation of α-synuclein (α-syn) into protein inclusions in degenerating brains. Increasing amounts of aggregated α-syn species indicate significant perturbation of cellular proteostasis. Altered proteostasis...
5.
Deckert A, Anders S, Morales I, De Allegri M, Nguyen H, Souares A, et al.
JMIR Public Health Surveill . 2024 Feb; 10:e57203. PMID: 38364221
[This corrects the article DOI: 10.2196/44204.].
6.
Kritsiligkou P, Bosch K, Shen T, Meurer M, Knop M, Dick T
Proc Natl Acad Sci U S A . 2023 Nov; 120(48):e2314043120. PMID: 37991942
Hydrogen peroxide (HO) sensing and signaling involves the reversible oxidation of particular thiols on particular proteins to modulate protein function in a dynamic manner. HO can be generated from various...
7.
Reinbold C, Kong K, Kats I, Khmelinskii A, Knop M
Methods Enzymol . 2023 Aug; 686:321-344. PMID: 37532406
N-terminal protein sequences and their proteolytic processing and modifications influence the stability and turnover of proteins by creating potential degrons for cellular proteolytic pathways. Understanding the impact of genetic perturbations...
8.
Kong K, Reinbold C, Knop M, Khmelinskii A
Methods Enzymol . 2023 Aug; 686:297-319. PMID: 37532405
Selective degradation of unnecessary or abnormal proteins by the ubiquitin-proteasome system is an essential part of proteostasis. Ubiquitin ligases recognize substrates of selective protein degradation and modify them with polyubiquitin...
9.
Deckert A, Anders S, Morales I, De Allegri M, Nguyen H, Souares A, et al.
JMIR Public Health Surveill . 2023 May; 9:e44204. PMID: 37235704
Background: The COVID-19 pandemic is characterized by rapid increases in infection burden owing to the emergence of new variants with higher transmissibility and immune escape. To date, monitoring the COVID-19...
10.
Lou D, Meurer M, Ovchinnikova S, Burk R, Denzler A, Herbst K, et al.
EMBO Rep . 2023 Mar; 24(5):e57162. PMID: 36951170
Throughout the SARS-CoV-2 pandemic, limited diagnostic capacities prevented sentinel testing, demonstrating the need for novel testing infrastructures. Here, we describe the setup of a cost-effective platform that can be employed...