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Michael Klann

Explore the profile of Michael Klann including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 130
Followers 0
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Recent Articles
1.
Ungricht R, Klann M, Horvath P, Kutay U
J Cell Biol . 2015 Jun; 209(5):687-703. PMID: 26056139
Newly synthesized membrane proteins are constantly sorted from the endoplasmic reticulum (ER) to various membranous compartments. How proteins specifically enrich at the inner nuclear membrane (INM) is not well understood....
2.
Klann M, Koeppl H
Phys Biol . 2013 Jul; 10(4):046005. PMID: 23820050
Modeling the spatiotemporal dynamics of biochemical reaction systems at single-molecule resolution has become feasible with the increase of computing power and is applied especially to cellular signal transduction. For an...
3.
Klann M, Ganguly A, Koeppl H
Bioinformatics . 2012 Sep; 28(18):i549-i555. PMID: 22962480
Motivation: Cellular signal transduction involves spatial-temporal dynamics and often stochastic effects due to the low particle abundance of some molecular species. Others can, however, be of high abundances. Such a...
4.
Klann M, Koeppl H
Int J Mol Sci . 2012 Jul; 13(6):7798-7827. PMID: 22837728
Cells are highly organized objects containing millions of molecules. Each biomolecule has a specific shape in order to interact with others in the complex machinery. Spatial dynamics emerge in this...
5.
Hiroi1 N, Klann M, Iba K, Heras Ciechomski P, Yamashita S, Tabira A, et al.
EURASIP J Bioinform Syst Biol . 2012 Jun; 2012:7. PMID: 22734658
: In our previous study, we introduced a combination methodology of Fluorescence Correlation Spectroscopy (FCS) and Transmission Electron Microscopy (TEM), which is powerful to investigate the effect of intracellular environment...
6.
Klann M, Koeppl H, Reuss M
PLoS One . 2012 Jan; 7(1):e29645. PMID: 22253752
The membrane trafficking machinery provides a transport and sorting system for many cellular proteins. We propose a mechanistic agent-based computer simulation to integrate and test the hypothesis of vesicle transport...
7.
Lapin A, Klann M, Reuss M
Adv Biochem Eng Biotechnol . 2010 Feb; 121:23-43. PMID: 20140659
Agent-based models are rigorous tools for simulating the interactions of individual entities, such as organisms or molecules within cells and assessing their effects on the dynamic behavior of the system...