Michael K K Leung
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Explore the profile of Michael K K Leung including associated specialties, affiliations and a list of published articles.
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15
Citations
441
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Recent Articles
1.
Leung M, Delong A, Frey B
Bioinformatics
. 2018 Apr;
34(17):2889-2898.
PMID: 29648582
Motivation: Processing of transcripts at the 3'-end involves cleavage at a polyadenylation site followed by the addition of a poly(A)-tail. By selecting which site is cleaved, the process of alternative...
2.
Leung M, Xiong H, Lee L, Frey B
Bioinformatics
. 2014 Jun;
30(12):i121-9.
PMID: 24931975
Motivation: Alternative splicing (AS) is a regulated process that directs the generation of different transcripts from single genes. A computational model that can accurately predict splicing patterns based on genomic...
3.
Maeda A, Leung M, Conroy L, Chen Y, Bu J, Lindsay P, et al.
PLoS One
. 2012 Aug;
7(8):e42133.
PMID: 22927920
Radiotherapy is a widely used cancer treatment. However, understanding how ionizing radiation affects tumor cells and their vasculature, particularly at cellular, subcellular, genetic, and protein levels, has been limited by...
4.
Chow J, Leung M, Jaffray D
Phys Med Biol
. 2012 May;
57(11):3323-31.
PMID: 22572475
This study investigated the secondary electron production from a gold nanoparticle (GNP) irradiated by monoenergetic electron beams using Monte Carlo (MC) simulation. Spherical GNPs with diameters of 2, 50 and...
5.
Leung M, Chow J, Chithrani B, Lee M, Oms B, Jaffray D
Med Phys
. 2011 Apr;
38(2):624-31.
PMID: 21452700
Purpose: The aim of this study is to understand the characteristics of secondary electrons generated from the interaction of gold nanoparticles (GNPs) with x-rays as a function of nanoparticle size...
6.
Chow J, Jiang R, Leung M
J Appl Clin Med Phys
. 2011 Feb;
12(1):3424.
PMID: 21330989
Although there are many works on evaluating dose calculations of the anisotropic analytical algorithm (AAA) using various homogeneous and heterogeneous phantoms, related work concerning dosimetry due to tangential photon beam...
7.
Chow J, Leung M, Lindsay P, Jaffray D
Med Phys
. 2010 Nov;
37(10):5322-9.
PMID: 21089767
Purpose: The impact of photon beam energy and tissue heterogeneities on dose distributions and dosimetric characteristics such as point dose, mean dose, and maximum dose was investigated in the context...
8.
Mariampillai A, Leung M, Jarvi M, Standish B, Lee K, Wilson B, et al.
Opt Lett
. 2010 Apr;
35(8):1257-9.
PMID: 20410985
We optimize speckle variance optical coherence tomography (svOCT) imaging of microvasculature in high and low bulk tissue motion scenarios. To achieve a significant level of image contrast, frame rates must...
9.
Munce N, Wright G, Mariampillai A, Standish B, Leung M, Tan L, et al.
J Biomed Opt
. 2010 Mar;
15(1):011103.
PMID: 20210429
We demonstrate the potential of a forward-looking Doppler optical coherence tomography (OCT) probe for color flow imaging in several commonly seen narrowed artery morphologies. As a proof of concept, we...
10.
Standish B, Lee K, Mariampillai A, Munce N, Leung M, Yang V, et al.
Phys Med Biol
. 2010 Jan;
55(3):615-22.
PMID: 20071753
A multichannel optical coherence tomography (multi-beam OCT) system and an in vivo endoscopic imaging probe were developed using a swept-source OCT system. The distal optics were micro-machined to produce a...