Michael J Shamblott
Overview
Explore the profile of Michael J Shamblott including associated specialties, affiliations and a list of published articles.
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23
Citations
360
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Recent Articles
1.
Shamblott M, ODriscoll M, Gomez D, McGuire D
Cell Commun Signal
. 2016 Sep;
14(1):23.
PMID: 27659207
Background: Reports of exocrine-to-endocrine reprogramming through expression or stabilization of the transcription factor neurogenin 3 (NGN3) have generated renewed interest in harnessing pancreatic plasticity for therapeutic applications. NGN3 is expressed...
2.
Gomez D, ODriscoll M, Sheets T, Hruban R, Oberholzer J, McGarrigle J, et al.
PLoS One
. 2015 Aug;
10(8):e0133862.
PMID: 26288179
Neurogenin 3 (NGN3) is necessary and sufficient for endocrine differentiation during pancreatic development and is expressed by a population of progenitor cells that give rise exclusively to hormone-secreting cells within...
3.
Pendleton J, Shamblott M, Gary D, Belegu V, Hurtado A, Malone M, et al.
Exp Neurol
. 2013 Apr;
247:113-21.
PMID: 23588220
CNS damage often results in demyelination of spared axons due to oligodendroglial cell death and dysfunction near the injury site. Although new oligodendroglia are generated following CNS injury and disease,...
4.
Barnett B, Ruiz-Cabello J, Hota P, Ouwerkerk R, Shamblott M, Lauzon C, et al.
Contrast Media Mol Imaging
. 2011 Aug;
6(4):251-9.
PMID: 21861285
In vivo imaging of engraftment and immunorejection of transplanted islets is critical for further clinical development, with (1)H MR imaging of superparamagnetic iron oxide-labeled cells being the current premier modality....
5.
Addis R, Prasad M, Yochem R, Zhan X, Sheets T, Axelman J, et al.
J Cell Biochem
. 2010 May;
111(2):391-401.
PMID: 20506506
OCT3/4 is a POU domain transcription factor that is critical for maintenance of pluripotency and self-renewal by embryonic stem (ES) cells and cells of the early mammalian embryo. It has...
6.
Crane J, Shamblott M, Axelman J, Hsu S, Levine M, Germain-Lee E
Clin Transl Sci
. 2010 May;
2(5):355-60.
PMID: 20443919
GNAS is a complex gene that through use of alternative first exons encodes signaling proteins Galpha(s) and XLalphas plus neurosecretory protein NESP55. Tissue-specific expression of these proteins is regulated through...
7.
Jones M, Chu C, Pendleton J, Betenbaugh M, Shiloach J, Baljinnyam B, et al.
Stem Cells Dev
. 2010 Apr;
19(12):1923-35.
PMID: 20367282
Human embryonic stem cells (hESC) require a balance of growth factors and signaling molecules to proliferate and retain pluripotency. Conditioned medium (CM) from a human embryonic germ-cell-derived cell culture, SDEC,...
8.
Locke J, Shamblott M, Cameron A
Adv Surg
. 2009 Oct;
43:35-51.
PMID: 19845168
ESLD affects millions of Americans, and HCV is a worldwide pandemic. Unfortunately, the ability to study liver disease and novel therapeutics experimentally in the laboratory is limited by an ongoing...
9.
Niu X, Gupta K, Yang J, Shamblott M, Levchenko A
J Cell Sci
. 2009 Feb;
122(Pt 5):600-10.
PMID: 19208767
Recent evidence from different research areas has revealed a novel mechanism of cell-cell communication by spontaneous intercellular transfer of cellular components (ICT). Here we studied this phenomenon by co-culturing different...
10.
Zhan X, Hill C, Brayton C, Shamblott M
Cloning Stem Cells
. 2008 Oct;
10(4):513-22.
PMID: 18823264
Various types of human cells have been tested as feeder cells for the undifferentiated growth of human embryonic stem cells (hESCs) in vitro. We report here the successful culture of...