Michael J Leone
Overview
Explore the profile of Michael J Leone including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
200
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Recent Articles
1.
Arokiaraj C, Leone M, Kleyman M, Chamessian A, Noh M, Phan B, et al.
Cell Rep
. 2024 Oct;
43(11):114876.
PMID: 39453813
Key mechanisms underlying chronic pain occur within the dorsal horn. Genome-wide association studies (GWASs) have identified genetic variants predisposed to chronic pain. However, most of these variants lie within regulatory...
2.
Leone M, Dashti H, Coughlin B, Tesh R, Quadri S, Bucklin A, et al.
Chronobiol Int
. 2023 May;
40(6):759-768.
PMID: 37144470
Intensive care units (ICUs) may disrupt sleep. Quantitative ICU studies of concurrent and continuous sound and light levels and timings remain sparse in part due to the lack of ICU...
3.
Ganglberger W, Krishnamurthy P, Quadri S, Tesh R, Bucklin A, Adra N, et al.
Front Netw Physiol
. 2023 Mar;
3:1120390.
PMID: 36926545
To measure sleep in the intensive care unit (ICU), full polysomnography is impractical, while activity monitoring and subjective assessments are severely confounded. However, sleep is an intensely networked state, and...
4.
Bucklin A, Ganglberger W, Quadri S, Tesh R, Adra N, Cardoso M, et al.
Sleep Breath
. 2022 Aug;
27(3):1013-1026.
PMID: 35971023
Purpose: Sleep-disordered breathing may be induced by, exacerbate, or complicate recovery from critical illness. Disordered breathing during sleep, which itself is often fragmented, can go unrecognized in the intensive care...
5.
Tesh R, Sun H, Jing J, Westmeijer M, Neelagiri A, Rajan S, et al.
Crit Care Explor
. 2022 Jan;
4(1):e0611.
PMID: 35072078
Design: This prospective, single-center, observational cohort study was conducted from August 2015 to December 2016 and October 2018 to December 2019. Setting: Academic medical center, all inpatient wards. Patients/subjects: Adult...
6.
van Sleuwen M, Sun H, Eckhardt C, Neelagiri A, Tesh R, Westmeijer M, et al.
Crit Care Med
. 2021 Sep;
50(1):e11-e19.
PMID: 34582420
Objectives: Delirium is a common and frequently underdiagnosed complication in acutely hospitalized patients, and its severity is associated with worse clinical outcomes. We propose a physiologically based method to quantify...
7.
Piantadosi A, Mukerji S, Ye S, Leone M, Freimark L, Park D, et al.
mBio
. 2021 Sep;
12(4):e0114321.
PMID: 34465023
Meningitis and encephalitis are leading causes of central nervous system (CNS) disease and often result in severe neurological compromise or death. Traditional diagnostic workflows largely rely on pathogen-specific tests, sometimes...
8.
Ganglberger W, Bucklin A, Tesh R, Cardoso M, Sun H, Leone M, et al.
Sleep Breath
. 2021 Aug;
26(3):1033-1044.
PMID: 34409545
Objective: Sleep-related respiratory abnormalities are typically detected using polysomnography. There is a need in general medicine and critical care for a more convenient method to detect sleep apnea automatically from...
9.
Mukerji S, Das S, Alabsi H, Brenner L, Jain A, Magdamo C, et al.
Front Neurol
. 2021 Apr;
12:642912.
PMID: 33897598
Patients with comorbidities are at increased risk for poor outcomes in COVID-19, yet data on patients with prior neurological disease remains limited. Our objective was to determine the odds of...
10.
Leone M, Sun H, Boutros C, Liu L, Ye E, Sullivan L, et al.
Sleep
. 2021 Mar;
44(8).
PMID: 33783511
Study Objectives: Age-related comorbidities and immune activation raise concern for advanced brain aging in people living with HIV (PLWH). The brain age index (BAI) is a machine learning model that...