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Michael J Herron

Explore the profile of Michael J Herron including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 419
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Recent Articles
1.
OConor M, Herron M, Nelson C, Barbet A, Crosby F, Burkhardt N, et al.
Pathog Dis . 2021 Jun; 79(5). PMID: 34077527
Anaplasma phagocytophilum (Ap), agent of human anaplasmosis, is an intracellular bacterium that causes the second most common tick-borne illness in North America. To address the lack of a genetic system...
2.
Crosby F, Munderloh U, Nelson C, Herron M, Lundgren A, Xiao Y, et al.
J Bacteriol . 2020 Sep; 202(23). PMID: 32928930
Many pathogenic bacteria translocate virulence factors into their eukaryotic hosts by means of type IV secretion systems (T4SS) spanning the inner and outer membranes. Genes encoding components of these systems...
3.
Nelson C, Herron M, Wang X, Baldridge G, Oliver J, Munderloh U
Front Vet Sci . 2020 Mar; 7:111. PMID: 32211428
The incidence of human diseases caused by tick-borne pathogens is increasing but little is known about the molecular interactions between the agents and their vectors and hosts. (Ap) is an...
4.
Oliva Chavez A, Herron M, Nelson C, Felsheim R, Oliver J, Burkhardt N, et al.
Ticks Tick Borne Dis . 2018 Nov; 10(2):482-494. PMID: 30466964
Mutational analysis is an efficient approach to identifying microbial gene function. Until recently, lack of an effective tool for Anaplasmataceae yielding reproducible results has created an obstacle to functional genomics,...
5.
Oliva Chavez A, Fairman J, Felsheim R, Nelson C, Herron M, Higgins L, et al.
PLoS Pathog . 2015 Nov; 11(11):e1005248. PMID: 26544981
Anaplasma phagocytophilum, the causative agent of Human Granulocytic Anaplasmosis (HGA), is an obligately intracellular α-proteobacterium that is transmitted by Ixodes spp ticks. However, the pathogen is not transovarially transmitted between...
6.
Chen G, Severo M, Sakhon O, Choy A, Herron M, Felsheim R, et al.
Infect Immun . 2012 Jul; 80(9):3194-205. PMID: 22753375
Anaplasma phagocytophilum is a tick-borne rickettsial pathogen that provokes an acute inflammatory response during mammalian infection. The illness caused by A. phagocytophilum, human granulocytic anaplasmosis, occurs irrespective of pathogen load...
7.
Kurtti T, Mattila J, Herron M, Felsheim R, Baldridge G, Burkhardt N, et al.
Insect Biochem Mol Biol . 2008 Aug; 38(10):963-8. PMID: 18722527
The genome project of the black legged tick, Ixodes scapularis, provides sequence data for testing gene function and regulation in this important pathogen vector. We tested Sleeping Beauty (SB), a...
8.
Nelson C, Herron M, Felsheim R, Schloeder B, Grindle S, Oliva Chavez A, et al.
BMC Genomics . 2008 Aug; 9:364. PMID: 18671858
Background: Anaplasma phagocytophilum (Ap) is an obligate intracellular bacterium and the agent of human granulocytic anaplasmosis, an emerging tick-borne disease. Ap alternately infects ticks and mammals and a variety of...
9.
Felsheim R, Herron M, Nelson C, Burkhardt N, Barbet A, Kurtti T, et al.
BMC Biotechnol . 2006 Nov; 6:42. PMID: 17076894
Background: Tick-borne pathogens cause emerging zoonoses, and include fastidious organisms such as Anaplasma phagocytophilum. Because of their obligate intracellular nature, methods for mutagenesis and transformation have not been available. Results:...
10.
Dugan V, Yabsley M, Tate C, Mead D, Munderloh U, Herron M, et al.
Vector Borne Zoonotic Dis . 2006 Jun; 6(2):192-207. PMID: 16796517
Anaplasma phagocytophilum, the causative agent of human granulocytotropic anaplasmosis, can infect white-tailed deer (WTD; Odocoileus virginianus), and this species is a crucial host for adult Ixodes scapularis, the primary vector...