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Michael J Crowther

Explore the profile of Michael J Crowther including associated specialties, affiliations and a list of published articles. Areas
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Articles 51
Citations 1048
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Recent Articles
1.
Entrop J, Jakobsen L, Crowther M, Clements M, Eloranta S, Dietrich C
Biom J . 2025 Feb; 67(1):e70038. PMID: 39967277
Recurrent events, for example, hospitalizations or drug prescriptions, are common in time-to-event research. One useful summary measure of the recurrent event process is the mean number of events. Methods for...
2.
Gasparini A, Crowther M, Hoogendijk E, Li F, Harhay M
Stat Med . 2025 Feb; 44(5):e10347. PMID: 39963907
Stepped wedge cluster-randomized trial (CRTs) designs randomize clusters of individuals to intervention sequences, ensuring that every cluster eventually transitions from a control period to receive the intervention under study by...
3.
Baech J, El-Galaly T, Entrop J, Glimelius I, Molin D, Godtfredsen S, et al.
EJHaem . 2024 Dec; 5(6):1190-1200. PMID: 39691265
Introduction: Congestive heart failure (CHF) is a known complication after anthracyclines and radiotherapy for classical Hodgkin lymphoma (cHL). Contemporary cHL treatment may be associated with less risk because radiotherapy use...
4.
John E, Crowther M, Didelez V, Sheehan N
Stat Methods Med Res . 2024 Dec; 34(1):3-25. PMID: 39659143
Instrumental variables (IVs) methods have recently gained popularity since, under certain assumptions, they may yield consistent causal effect estimators in the presence of unmeasured confounding. Existing simulation studies that evaluate...
5.
Freeman S, Sutton A, Cooper N, Gasparini A, Crowther M, Hawkins N
Res Synth Methods . 2024 May; 15(5):780-801. PMID: 38772906
Background: Traditionally, meta-analysis of time-to-event outcomes reports a single pooled hazard ratio assuming proportional hazards (PH). For health technology assessment evaluations, hazard ratios are frequently extrapolated across a lifetime horizon....
6.
Creignou M, Bernard E, Gasparini A, Tranberg A, Todisco G, Moura P, et al.
J Intern Med . 2024 Apr; 296(1):53-67. PMID: 38654517
Background: The Molecular International Prognostic Scoring System (IPSS-M) is the new gold standard for diagnostic outcome prediction in patients with myelodysplastic syndromes (MDS). This study was designed to assess the...
7.
Curnow E, Hughes R, Birnie K, Tilling K, Crowther M
Stat Med . 2024 Jan; 43(6):1238-1255. PMID: 38258282
In clinical studies, multi-state model (MSM) analysis is often used to describe the sequence of events that patients experience, enabling better understanding of disease progression. A complicating factor in many...
8.
Broomfield J, Abrams K, Freeman S, Latimer N, Rutherford M, Crowther M
Stat Med . 2023 Nov; 43(1):184-200. PMID: 37932874
Multi-state survival models are used to represent the natural history of a disease, forming the basis of a health technology assessment comparing a novel treatment to current practice. Constructing such...
9.
Skourlis N, Crowther M, Andersson T, Lu D, Lambe M, Lambert P
BMC Med Res Methodol . 2023 Apr; 23(1):87. PMID: 37038100
Background: Multi-state models are used to study several clinically meaningful research questions. Depending on the research question of interest and the information contained in the data, different multi-state structures and...
10.
Weibull C, Wasterlid T, Wahlin B, Andersson P, Ekberg S, Lockmer S, et al.
Hemasphere . 2023 Feb; 7(3):e838. PMID: 36844185
In follicular lymphoma (FL), progression of disease ≤24 months (POD24) has emerged as an important prognostic marker for overall survival (OS). We aimed to investigate survival more broadly by timing...