Michael J Coyne
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Explore the profile of Michael J Coyne including associated specialties, affiliations and a list of published articles.
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55
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1580
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Recent Articles
1.
Sheahan M, Flores K, Coyne M, Garcia-Bayona L, Chatzidaki-Livanis M, Holst A, et al.
Science
. 2024 Oct;
386(6720):414-420.
PMID: 39446952
DNA transfer is ubiquitous in the human gut microbiota, especially among species of the order Bacteroidales. In silico analyses have revealed hundreds of mobile genetic elements shared between these species,...
2.
Zhang Z, Cole C, Coyne M, Lin H, Dylla N, Smith R, et al.
Cell Host Microbe
. 2024 Sep;
32(10):1853-1867.e5.
PMID: 39293438
Species of the Bacteroidales order are among the most abundant and stable bacterial members of the human gut microbiome, with diverse impacts on human health. We cultured and sequenced the...
3.
Abrahamsen H, Sanford T, Collamore C, Johnstone B, Coyne M, Garcia-Bayona L, et al.
Nat Commun
. 2024 Jun;
15(1):5028.
PMID: 38866748
Cholesterol-dependent cytolysins (CDCs) comprise a large family of pore-forming toxins produced by Gram-positive bacteria, which are used to attack eukaryotic cells. Here, we functionally characterize a family of 2-component CDC-like...
4.
Garcia-Bayona L, Said N, Coyne M, Flores K, Elmekki N, Sheahan M, et al.
bioRxiv
. 2024 May;
PMID: 38746121
Although horizontal gene transfer is pervasive in the intestinal microbiota, we understand only superficially the roles of most exchanged genes and how the mobile repertoire affects community dynamics. Similarly, little...
5.
Zhang Z, Cole C, Coyne M, Lin H, Dylla N, Smith R, et al.
bioRxiv
. 2024 Mar;
PMID: 38496653
Species of the Bacteroidales order are among the most abundant and stable bacterial members of the human gut microbiome with diverse impacts on human health. While Bacteroidales strains and species...
6.
Carasso S, Zaatry R, Hajjo H, Kadosh-Kariti D, Ben-Assa N, Naddaf R, et al.
Cell Host Microbe
. 2024 Feb;
32(3):322-334.e9.
PMID: 38423015
Reversible genomic DNA inversions control the expression of numerous gut bacterial molecules, but how this impacts disease remains uncertain. By analyzing metagenomic samples from inflammatory bowel disease (IBD) cohorts, we...
7.
Sheahan M, Coyne M, Flores K, Garcia-Bayona L, Chatzidaki-Livanis M, Sundararajan A, et al.
bioRxiv
. 2023 Sep;
PMID: 37662397
DNA transfer is ubiquitous in the gut microbiota, especially among species of Bacteroidales. analyses have revealed hundreds of mobile genetic elements shared between these species, yet little is known about...
8.
Evans J, McEneany V, Coyne M, Caldwell E, Sheahan M, Von S, et al.
Nat Commun
. 2022 Jul;
13(1):4258.
PMID: 35871068
Phocaeicola vulgatus is one of the most abundant and ubiquitous bacterial species of the human gut microbiota, yet a comprehensive analysis of antibacterial toxin production by members of this species...
9.
Analysis of Effector and Immunity Proteins of the GA2 Type VI Secretion Systems of Gut Bacteroidales
Bao H, Coyne M, Garcia-Bayona L, Comstock L
J Bacteriol
. 2022 Jun;
204(7):e0012222.
PMID: 35735993
Three distinct genetic architectures (GAs) of Type VI secretion systems (T6SSs) have been described in gut Bacteroidales species, each with unique genes and characteristics. Unlike the GA3 T6SSs, potent antagonism...
10.
Coyne M, Drake C, McCrann D, Kincaid D
Vet Comp Oncol
. 2022 Jun;
20(4):846-853.
PMID: 35718995
Following the introduction of the symmetric dimethylarginine (SDMA) immunoassay, cases were reported where the SDMA concentration was markedly increased above the reference interval (RI) with neither concurrent increases in serum...