Michael J Conboy
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Explore the profile of Michael J Conboy including associated specialties, affiliations and a list of published articles.
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42
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3870
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Recent Articles
11.
Kim D, Kim S, Sung A, Patel N, Wong N, Conboy M, et al.
Transl Neurodegener
. 2022 Mar;
11(1):16.
PMID: 35272709
Background: Amyotrophic lateral sclerosis (ALS) is characterized by a progressive loss of motor neurons (MNs), leading to paralysis, respiratory failure and death within 2-5 years of diagnosis. The exact mechanisms...
12.
Fernandez C, Burgos A, Morales D, Rosales-Rojas R, Canelo J, Vergara-Jaque A, et al.
FASEB J
. 2021 Apr;
35(5):e21597.
PMID: 33908663
Aging is a gradual biological process characterized by a decrease in cellular and organism functions. Aging-related processes involve changes in the expression and activity of several proteins. Here, we identified...
13.
DeCastro J, Littig J, Chou P, Mack-Onyeike J, Srinivasan A, Conboy M, et al.
Molecules
. 2021 Jan;
26(3).
PMID: 33498573
As the fields of aging and neurological disease expand to liquid biopsies, there is a need to identify informative biomarkers for the diagnosis of neurodegeneration and other age-related disorders such...
14.
Mehdipour M, Mehdipour T, Skinner C, Wong N, Liu C, Chen C, et al.
Geroscience
. 2020 Nov;
43(1):1-18.
PMID: 33191466
Our recent study has established that young blood factors are not causal, nor necessary, for the systemic rejuvenation of mammalian tissues. Instead, a procedure referred to as neutral blood exchange...
15.
Kiprov D, Conboy M, Conboy I
Transfus Apher Sci
. 2020 Jul;
59(4):102856.
PMID: 32653199
No abstract available.
16.
Liu Y, Conboy M, Mehdipour M, Liu Y, Tran T, Blotnick A, et al.
Nat Commun
. 2020 Jul;
11(1):3550.
PMID: 32651369
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
17.
Mehdipour M, Skinner C, Wong N, Lieb M, Liu C, Etienne J, et al.
Aging (Albany NY)
. 2020 Jun;
12(10):8790-8819.
PMID: 32474458
Heterochronic blood sharing rejuvenates old tissues, and most of the studies on how this works focus on young plasma, its fractions, and a few youthful systemic candidates. However, it was...
18.
Etienne J, Liu C, Skinner C, Conboy M, Conboy I
Skelet Muscle
. 2020 Feb;
10(1):4.
PMID: 32033591
Skeletal muscle is among the most age-sensitive tissues in mammal organisms. Significant changes in its resident stem cells (i.e., satellite cells, SCs), differentiated cells (i.e., myofibers), and extracellular matrix cause...
19.
Mehdipour M, Etienne J, Chen C, Gathwala R, Rehman M, Kato C, et al.
Aging (Albany NY)
. 2019 Aug;
11(15):5628-5645.
PMID: 31422380
We hypothesize that altered intensities of a few morphogenic pathways account for most/all the phenotypes of aging. Investigating this has revealed a novel approach to rejuvenate multiple mammalian tissues by...
20.
Sadlowski C, Balderston S, Sandhu M, Hajian R, Liu C, Tran T, et al.
Lab Chip
. 2018 Sep;
18(21):3230-3238.
PMID: 30239548
Studies of heterochronic parabiosis, where two animals of different ages are joined surgically, provided proof-of-principle results that systemic proteins have broad age-specific effects on tissue health and repair. In an...