Michael J Bray
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Explore the profile of Michael J Bray including associated specialties, affiliations and a list of published articles.
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19
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173
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Recent Articles
1.
Chen T, Pham G, Fox L, Adler N, Wang X, Zhang J, et al.
EBioMedicine
. 2024 Nov;
110:105441.
PMID: 39520911
Background: Lung cancer and tobacco use pose significant global health challenges, necessitating a comprehensive translational roadmap for improved prevention strategies such as cancer screening and tobacco treatment, which are currently...
2.
Breeyear J, Mautz B, Keaton J, Hellwege J, Torstenson E, Liang J, et al.
Am J Hum Genet
. 2024 Apr;
111(5):954-965.
PMID: 38614075
Variability in quantitative traits has clinical, ecological, and evolutionary significance. Most genetic variants identified for complex quantitative traits have only a detectable effect on the mean of trait. We have...
3.
Chen T, Pham G, Fox L, Adler N, Wang X, Zhang J, et al.
medRxiv
. 2024 Apr;
PMID: 38562690
Background: Lung cancer and tobacco use pose significant global health challenges, necessitating a comprehensive translational roadmap for improved prevention strategies. Polygenic risk scores (PRSs) are powerful tools for patient risk...
4.
Bourdon J, Dorsey A, Zalik M, Pietka A, Salyer P, Bray M, et al.
BMC Med Genomics
. 2021 May;
14(1):139.
PMID: 34039360
Background: The use of genetically-informed personalized risk information for behavioral disorders, namely smoking and smoking-related behaviors, is a promising yet understudied area. The Genetics and Smoking Risk Profile, or RiskProfile,...
5.
Bray M, Chen L, Fox L, Ma Y, Grucza R, Hartz S, et al.
Nicotine Tob Res
. 2021 May;
23(12):2110-2116.
PMID: 33991188
Introduction: The purpose of this study is to examine the predictive utility of polygenic risk scores (PRSs) for smoking behaviors. Aims And Methods: Using summary statistics from the Sequencing Consortium...
6.
Quach B, Bray M, Gaddis N, Liu M, Palviainen T, Minica C, et al.
Nat Commun
. 2020 Nov;
11(1):5562.
PMID: 33144568
Cigarette smoking is the leading cause of preventable morbidity and mortality. Genetic variation contributes to initiation, regular smoking, nicotine dependence, and cessation. We present a Fagerström Test for Nicotine Dependence...
7.
Bray M, Chen L, Fox L, Hancock D, Culverhouse R, Hartz S, et al.
Genet Epidemiol
. 2020 Aug;
44(7):748-758.
PMID: 32803792
Smoking is a major contributor to lung cancer and chronic obstructive pulmonary disease (COPD). Two of the strongest genetic associations of smoking-related phenotypes are the chromosomal regions 15q25.1, encompassing the...
8.
Bray M, Davis L, Torstenson E, Jones S, Edwards T, Velez Edwards D
Hum Hered
. 2019 Sep;
84(2):73-81.
PMID: 31480066
Background: Heritability estimates (including twin and single nucleotide polymorphism [SNP]-based heritability studies) for fibroids have been inconsistent across prior studies ranging between 9 and 69%. These inconsistencies are due to...
9.
Edwards T, Giri A, Hellwege J, Hartmann K, Stewart E, Jeff J, et al.
Front Genet
. 2019 Jun;
10:511.
PMID: 31249589
Uterine fibroids affect up to 77% of women by menopause and account for up to $34 billion in healthcare costs each year. Although fibroid risk is heritable, genetic risk for...
10.
Bray M, Wellons M, Jones S, Torstenson E, Edwards T, Velez Edwards D
Fertil Steril
. 2018 Sep;
110(4):737-745.e34.
PMID: 30196971
Objective: To identify, through genome-wide association studies, genetic loci that associate with differences in fibroid size and number in a population of African American and European American women. Design: Cross-sectional...