Michael J Bertoldo
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Explore the profile of Michael J Bertoldo including associated specialties, affiliations and a list of published articles.
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33
Citations
567
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Recent Articles
1.
Ho W, Marinova M, Listijono D, Bertoldo M, Richani D, Kim L, et al.
EMBO Mol Med
. 2024 Aug;
16(10):2583-2618.
PMID: 39169162
Chemotherapy induced ovarian failure and infertility is an important concern in female cancer patients of reproductive age or younger, and non-invasive, pharmacological approaches to maintain ovarian function are urgently needed....
2.
Aflatounian A, Rodriguez Paris V, Richani D, Edwards M, Cochran B, Ledger W, et al.
Mol Metab
. 2022 Sep;
65:101583.
PMID: 36096453
Polycystic ovary syndrome (PCOS) is a common endocrine disorder, defined by reproductive and endocrine abnormalities, with metabolic dysregulation including obesity, insulin resistance and hepatic steatosis. Recently, it was found that...
3.
Habibalahi A, Campbell J, Bertoldo M, Mahbub S, Goss D, Ledger W, et al.
Biomedicines
. 2022 Jul;
10(7).
PMID: 35884850
The purpose of this study is to develop a deep radiomic signature based on an artificial intelligence (AI) model. This radiomic signature identifies oocyte morphological changes corresponding to reproductive aging...
4.
Campbell J, Mahbub S, Bertoldo M, Habibalahi A, Goss D, Ledger W, et al.
Biogerontology
. 2022 Feb;
23(2):237-249.
PMID: 35211812
Increasing age has a major detrimental impact on female fertility, which, with an ageing population, has major sociological implications. This impact is primarily mediated through deteriorating quality of the oocyte....
5.
Faure M, Khoueiry R, Quanico J, Acloque H, Guerquin M, Bertoldo M, et al.
Front Endocrinol (Lausanne)
. 2021 Nov;
12:750145.
PMID: 34745014
Metformin is a drug used for the treatment of type 2 diabetes and disorders associated with insulin resistance. Metformin is also used in the treatment of pregnancy disorders such as...
6.
Rodriguez Paris V, Edwards M, Aflatounian A, Bertoldo M, Ledger W, Handelsman D, et al.
J Endocr Soc
. 2021 May;
5(6):bvab060.
PMID: 34056500
Polycystic ovary syndrome (PCOS) is a common and heterogeneous disorder; however, the etiology and pathogenesis of PCOS are poorly understood and current management is symptom-based. Defining the pathogenesis of PCOS...
7.
Volckmar X, Vallejo M, Bertoldo M, Nguyen Q, Handelsman D, Chisholm O, et al.
Clin Pharmacol Ther
. 2021 Apr;
111(2):382-390.
PMID: 33826770
We reviewed the available animal and human reproductive function studies of recently approved noncytotoxic oncology drugs. We reviewed the oncofertility information in the prescribing information for the US Food and...
8.
Sucquart I, Nagarkar R, Edwards M, Rodriguez Paris V, Aflatounian A, Bertoldo M, et al.
Endocrinology
. 2021 Feb;
162(5).
PMID: 33522579
Polycystic ovary syndrome (PCOS) is a prevalent endocrine condition characterized by a range of endocrine, reproductive, and metabolic abnormalities. At present, management of women with PCOS is suboptimal as treatment...
9.
Bertoldo M, Rodriguez Paris V, Gook D, Edwards M, Wu K, Liang C, et al.
Reproduction
. 2020 Dec;
161(2):215-226.
PMID: 33320829
Ovarian tissue cryopreservation and future transplantation is the only strategy to preserve the fertility of young female adolescent and prepubertal patients. The primary challenge to ovarian graft longevity is the...
10.
Bertoldo M, Smitz J, Wu L, Lee H, Woodruff T, Gilchrist R
Trends Endocrinol Metab
. 2020 Aug;
31(10):708-711.
PMID: 32807599
Childhood cancer patients undergoing cancer therapy can be rendered infertile during adulthood. With more girls surviving cancer, fertility preservation in young cancer patients is a major clinical challenge. Advances in...