Michael Hayward
Overview
Explore the profile of Michael Hayward including associated specialties, affiliations and a list of published articles.
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23
Citations
1273
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Recent Articles
1.
Yuan C, Rayasam A, Moe A, Hayward M, Wells C, Szabo A, et al.
Nat Commun
. 2023 Dec;
14(1):7963.
PMID: 38042840
Paneth cell metaplasia (PCM) typically arises in pre-existing gastrointestinal (GI) diseases; however, the mechanistic pathway that induces metaplasia and whether PCM is initiated exclusively by disorders intrinsic to the GI...
2.
Fung C, Fraser L, Barron G, Gologorsky M, Atkinson S, Gerrick E, et al.
Proc Natl Acad Sci U S A
. 2023 May;
120(23):e2216908120.
PMID: 37253002
Succinate produced by the commensal protist () stimulates chemosensory tuft cells, resulting in intestinal type 2 immunity. Tuft cells express the succinate receptor SUCNR1, yet this receptor does not mediate...
3.
Sadler K, Atkinson S, Ehlers V, Waltz T, Hayward M, Rodriguez Garcia D, et al.
bioRxiv
. 2023 May;
PMID: 37163080
Pain is a debilitating symptom and leading reason for hospitalization of individuals with sickle cell disease. Chronic sickle cell pain is poorly managed because the biological basis is not fully...
4.
Zenga J, Atkinson S, Yen T, Massey B, Stadler M, Bruening J, et al.
EBioMedicine
. 2022 Jun;
81:104099.
PMID: 35671624
Background: Head and neck cancer (HNC) surgery remains an important component of management but is associated with a high rate of surgical site infection (SSI). We aimed to assess the...
5.
Frietze K, Brown A, Das D, Franks R, Cunningham J, Hayward M, et al.
Autophagy
. 2021 May;
18(1):142-160.
PMID: 33966599
Nonalcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease globally. NAFLD is a consequence of fat accumulation in the liver leading to lipotoxicity. Increasing evidence has...
6.
Yang M, Gallo-Ebert C, Hayward M, Liu W, McDonough V, Nickels Jr J
Mol Cell Biol
. 2020 Jun;
40(16).
PMID: 32482798
Genome-wide association studies (GWAS) have linked single-nucleotide polymorphisms (SNPs) with type 2 diabetes (T2D). Mice overexpressing have elevated cholesterol levels when fed a diet that induces hepatic steatosis. These and...
7.
Bajaj J, Salzman N, Acharya C, Takei H, Kakiyama G, Fagan A, et al.
JCI Insight
. 2019 Nov;
4(24).
PMID: 31751317
BACKGROUNDHepatic encephalopathy (HE) is associated with poor outcomes. A prior randomized, pilot trial demonstrated safety after oral capsular fecal microbial transplant (FMT) in HE, with favorable changes in microbial composition...
8.
Bajaj J, Salzman N, Acharya C, Sterling R, White M, Gavis E, et al.
Hepatology
. 2019 May;
70(5):1690-1703.
PMID: 31038755
Hepatic encephalopathy (HE) can cause major morbidity despite standard of care (SOC; rifaximin/lactulose). Fecal microbial transplant (FMT) enemas postantibiotics are safe, but the effect of FMT without antibiotics using the...
9.
Banla L, Pickrum A, Hayward M, Kristich C, Salzman N
Infect Immun
. 2019 Feb;
87(5).
PMID: 30804098
The human gastrointestinal tract (GIT) is inhabited by a dense microbial community of symbionts. Enterococci are among the earliest members of this community and remain core members of the GIT...
10.
Geldart K, Kommineni S, Forbes M, Hayward M, Dunny G, Salzman N, et al.
Bioeng Transl Med
. 2018 Nov;
3(3):197-208.
PMID: 30377660
Vancomycin-resistant (VRE) poses a serious threat in hospitals where they densely colonize the intestinal tracts of patients. In vulnerable hosts, these pathogens may translocate to the bloodstream and become lethal....