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Michael Hausding

Explore the profile of Michael Hausding including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 31
Citations 1425
Followers 0
Related Specialties
Endocrinology
Allergy & Immunology
Pharmacology
Top 10 Co-Authors
Andreas Daiber
Thomas Munzel
Matthias Oelze
Eberhard Schulz
Swenja Kroller-Schon
Philip Wenzel
Susetta Finotto
Sebastian Steven
Maike Knorr
Thomas Jansen
Published In
Arterioscler Thromb Vasc Biol
Basic Res Cardiol
Oxid Med Cell Longev
Int Immunol
Cardiovasc Res
Affiliations
Soon will be listed here.
Recent Articles
1.
The Endothelin Receptor Antagonist Macitentan Improves Isosorbide-5-Mononitrate (ISMN) and Isosorbide Dinitrate (ISDN) Induced Endothelial Dysfunction, Oxidative Stress, and Vascular Inflammation
Steven S, Oelze M, Hausding M, Roohani S, Kashani F, Kroller-Schon S, et al.
Oxid Med Cell Longev . 2019 Jan; 2018:7845629. PMID: 30687454
Objective: Organic nitrates such as isosorbide-5-mononitrate (ISMN) and isosorbide dinitrate (ISDN) are used for the treatment of patients with chronic symptomatic stable coronary artery disease and chronic congestive heart failure....
2.
CD40L controls obesity-associated vascular inflammation, oxidative stress, and endothelial dysfunction in high fat diet-treated and db/db mice
Steven S, Dib M, Hausding M, Kashani F, Oelze M, Kroller-Schon S, et al.
Cardiovasc Res . 2017 Oct; 114(2):312-323. PMID: 29036612
Aims: CD40 ligand (CD40L) signaling controls vascular oxidative stress and related dysfunction in angiotensin-II-induced arterial hypertension by regulating vascular immune cell recruitment and platelet activation. Here we investigated the role...
3.
Gliptins Suppress Inflammatory Macrophage Activation to Mitigate Inflammation, Fibrosis, Oxidative Stress, and Vascular Dysfunction in Models of Nonalcoholic Steatohepatitis and Liver Fibrosis
Wang X, Hausding M, Weng S, Kim Y, Steven S, Klein T, et al.
Antioxid Redox Signal . 2017 Jun; 28(2):87-109. PMID: 28635324
Aims: Nonalcoholic steatohepatitis (NASH) is characterized by steatosis, panlobular inflammation, liver fibrosis, and increased cardiovascular mortality. Dipeptidyl peptidase-4 inhibitors (gliptins) are indirect glucagon-like peptide 1 agonists with antidiabetic and anti-inflammatory...
4.
Role of Protein Kinase C and Nox2-Derived Reactive Oxygen Species Formation in the Activation and Maturation of Dendritic Cells by Phorbol Ester and Lipopolysaccharide
Stein J, Steven S, Bros M, Sudowe S, Hausding M, Oelze M, et al.
Oxid Med Cell Longev . 2017 May; 2017:4157213. PMID: 28458776
. Activation/maturation of dendritic cells (DCs) plays a central role in adaptive immune responses by antigen processing and (cross-) activation of T cells. There is ongoing discussion on the role...
5.
Gliptin and GLP-1 analog treatment improves survival and vascular inflammation/dysfunction in animals with lipopolysaccharide-induced endotoxemia
Steven S, Hausding M, Kroller-Schon S, Mader M, Mikhed Y, Stamm P, et al.
Basic Res Cardiol . 2015 Jan; 110(2):6. PMID: 25600227
Dipeptidyl peptidase (DPP)-4 inhibitors are used to treat hyperglycemia by increasing the incretin glucagon-like peptide-1 (GLP-1). Previous studies showed anti-inflammatory and antiatherosclerotic effects of DPP-4 inhibitors. Here, we compared the...
6.
The sodium-glucose co-transporter 2 inhibitor empagliflozin improves diabetes-induced vascular dysfunction in the streptozotocin diabetes rat model by interfering with oxidative stress and glucotoxicity
Oelze M, Kroller-Schon S, Welschof P, Jansen T, Hausding M, Mikhed Y, et al.
PLoS One . 2014 Nov; 9(11):e112394. PMID: 25402275
Objective: In diabetes, vascular dysfunction is characterized by impaired endothelial function due to increased oxidative stress. Empagliflozin, as a selective sodium-glucose co-transporter 2 inhibitor (SGLT2i), offers a novel approach for...
7.
In vitro and in vivo characterization of a new organic nitrate hybrid drug covalently bound to pioglitazone
Knorr M, Hausding M, Pfeffer A, Jurk K, Jansen T, Schwierczek K, et al.
Pharmacology . 2014 Jun; 93(5-6):203-15. PMID: 24923291
Background/aims: Organic nitrates represent a group of nitrovasodilators that are clinically used for the treatment of ischemic heart disease. The new compound CLC-3000 is an aminoethyl nitrate (AEN) derivative of...
8.
Glutathione peroxidase-1 deficiency potentiates dysregulatory modifications of endothelial nitric oxide synthase and vascular dysfunction in aging
Oelze M, Kroller-Schon S, Steven S, Lubos E, Doppler C, Hausding M, et al.
Hypertension . 2013 Dec; 63(2):390-6. PMID: 24296279
Recently, we demonstrated that gene ablation of mitochondrial manganese superoxide dismutase and aldehyde dehydrogenase-2 markedly contributed to age-related vascular dysfunction and mitochondrial oxidative stress. The present study has sought to...
9.
CD40L contributes to angiotensin II-induced pro-thrombotic state, vascular inflammation, oxidative stress and endothelial dysfunction
Hausding M, Jurk K, Daub S, Kroller-Schon S, Stein J, Schwenk M, et al.
Basic Res Cardiol . 2013 Sep; 108(6):386. PMID: 24061433
CD40 ligand (CD40L) is involved in the vascular infiltration of immune cells and pathogenesis of atherosclerosis. Additionally, T cell CD40L release causes platelet, dendritic cell and monocyte activation in thrombosis....
10.
Molecular mechanisms of the crosstalk between mitochondria and NADPH oxidase through reactive oxygen species-studies in white blood cells and in animal models
Kroller-Schon S, Steven S, Kossmann S, Scholz A, Daub S, Oelze M, et al.
Antioxid Redox Signal . 2013 Jul; 20(2):247-66. PMID: 23845067
Aims: Oxidative stress is involved in the development of cardiovascular disease. There is a growing body of evidence for a crosstalk between different enzymatic sources of oxidative stress. With the...