Michael Hamilton
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Explore the profile of Michael Hamilton including associated specialties, affiliations and a list of published articles.
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46
Citations
865
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Recent Articles
1.
Barber A, Quintero C, Hamilton M, Rajbhandari N, Sasik R, Zhang Y, et al.
Elife
. 2025 Mar;
13.
PMID: 40047406
Despite advances in therapeutic approaches, lung cancer remains the leading cause of cancer-related deaths. To understand the molecular programs underlying lung cancer initiation and maintenance, we focused on stem cell...
2.
deVries M, McGillis Hall L, Dainty K, Fan M, Tscheng D, Hamilton M, et al.
Res Social Adm Pharm
. 2025 Jan;
21(4):228-238.
PMID: 39818532
Purpose: Diversion or theft of controlled substances is a recognized problem affecting healthcare systems globally. The purpose of this study was to develop a framework for identifying and characterizing system...
3.
Spinler K, Hamilton M, Bajaj J, Shima Y, Diaz E, Kritzik M, et al.
bioRxiv
. 2024 Jan;
PMID: 38234720
Myeloid leukemias, diseases marked by aggressiveness and poor outcomes, are frequently triggered by oncogenic translocations. In the case of chronic myelogenous leukemia (CML) the BCR-ABL fusion initiates chronic phase disease...
4.
Rajbhandari N, Hamilton M, Quintero C, Ferguson L, Fox R, Schurch C, et al.
Cancer Cell
. 2023 Oct;
41(11):1989-2005.e9.
PMID: 37802055
Identifying the cells from which cancers arise is critical for understanding the molecular underpinnings of tumor evolution. To determine whether stem/progenitor cells can serve as cells of origin, we created...
5.
Mallakin M, Dery C, Woldemariam Y, Hamilton M, Corace K, Pauly B, et al.
BMC Public Health
. 2023 Apr;
23(1):774.
PMID: 37101181
Background: In response to the rise in opioid-related deaths, communities across Ontario have developed opioid or overdose response plans to address issues at the local level. Public Health Ontario (PHO)...
6.
Ferguson L, Gatchalian J, McDermott M, Nakamura M, Chambers K, Rajbhandari N, et al.
Nat Commun
. 2023 Jan;
14(1):292.
PMID: 36653361
Pancreatic cancer is characterized by extensive resistance to conventional therapies, making clinical management a challenge. Here we map the epigenetic dependencies of cancer stem cells, cells that preferentially evade therapy...
7.
Khorasheh T, Bennett AbuAyyash C, Mallakin M, Sellen K, Corace K, Pauly B, et al.
BMC Public Health
. 2022 Jul;
22(1):1390.
PMID: 35854231
Background: Many communities across North America are coming together to develop comprehensive plans to address and respond to the escalating overdose crisis, largely driven by an increasingly toxic unregulated drug...
8.
Luning Prak D, Hamilton M, Banados R, Cowart J
Data Brief
. 2022 Feb;
41:107849.
PMID: 35146085
In this work, the density, viscosity, speed of sound, flash point, and surface tension of mixtures of military jet fuel JP-5 and biodiesels were measured at various temperatures. The biodiesels...
9.
Perera N, Tsey K, Heyeres M, Whiteside M, Baird L, McCalman J, et al.
Int J Equity Health
. 2022 Jan;
21(1):2.
PMID: 35012602
Background: An Aboriginal-developed empowerment and social and emotional wellbeing program, known as Family Wellbeing (FWB), has been found to strengthen the protective factors that help Indigenous Australians to deal with...
10.
Bajaj J, Hamilton M, Shima Y, Chambers K, Spinler K, Van Nostrand E, et al.
Nat Cancer
. 2021 Jun;
1(4):410-422.
PMID: 34109316
Aggressive myeloid leukemias such as blast crisis chronic myeloid leukemia and acute myeloid leukemia remain highly lethal. Here we report a genome-wide in vivo CRISPR screen to identify new dependencies...