Michael H Shearer
Overview
Explore the profile of Michael H Shearer including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
194
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Recent Articles
1.
Aldrich J, Shearer M, Lowe D, Winn R, Jumper C, Kennedy R, et al.
Cancer Immunol Immunother
. 2012 Aug;
62(2):371-82.
PMID: 22926061
The central role of CD4+ T lymphocytes in mediating DNA vaccine-induced tumor immunity against the viral oncoprotein simian virus 40 (SV40) large tumor antigen (Tag) has previously been described by...
2.
Aldrich J, Lowe D, Shearer M, Winn R, Jumper C, Bright R, et al.
J Virol
. 2011 May;
85(14):7216-24.
PMID: 21593176
A mechanistic analysis of tumor immunity directed toward the viral oncoprotein simian virus 40 (SV40) large tumor antigen (Tag) has previously been described by our laboratory for scenarios of recombinant...
3.
Aldrich J, Lowe D, Shearer M, Winn R, Jumper C, Kennedy R
Clin Dev Immunol
. 2010 Oct;
2010:697158.
PMID: 20936120
The employment of the immune system to treat malignant disease represents an active area of biomedical research. The specificity of the immune response and potential for establishing long-term tumor immunity...
4.
Lowe D, Shearer M, Aldrich J, Winn R, Jumper C, Kennedy R
J Virol
. 2010 Jul;
84(19):10121-30.
PMID: 20668083
We examined properties of the innate immune response against the tumor-specific antigen simian virus 40 (SV40) large tumor antigen (Tag) following experimental pulmonary metastasis in naive mice. Approximately 14 days...
5.
Filleur S, Hirsch J, Wille A, Schon M, Sell C, Shearer M, et al.
Cancer Cell Int
. 2009 Nov;
9:28.
PMID: 19906297
Background: The gene encoding integrator complex subunit 6 (INTS6), previously known as deleted in cancer cells 1 (DICE1, OMIM 604331) was found to be frequently affected by allelic deletion and...
6.
Lowe D, Shearer M, Jumper C, Bright R, Kennedy R
J Virol
. 2009 Nov;
84(2):883-93.
PMID: 19889780
The required activities of CD4(+) T cells and antibody against the virally encoded oncoprotein simian virus 40 (SV40) Tag have previously been demonstrated by our laboratory to be mediators in...
7.
Westfall L, Shearer M, Jumper C, White G, Papin J, Eberle R, et al.
Virology
. 2008 May;
377(1):54-62.
PMID: 18485439
Simian virus 40 (SV40) is a polyomavirus for which non-human primates are the permissive host. The baboon (Papio spp.) is an old world monkey that is used in a variety...
8.
Chiriva-Internati M, Grizzi F, Weidanz J, Ferrari R, Yuefei Y, Velez B, et al.
J Immunol Methods
. 2007 Mar;
321(1-2):86-93.
PMID: 17336323
No experimental animal model employing a primary human ovarian carcinoma (OC) cell line is presently available that tracks the progression of this cell line with an identifiable marker. This hinders...
9.
Lowe D, Shearer M, Jumper C, Bright R, Kennedy R
J Virol
. 2006 Nov;
81(3):1313-8.
PMID: 17108042
Simian virus 40 (SV40) large tumor antigen (Tag) represents a virus-encoded tumor-specific antigen expressed in many types of human cancers and a potential immunologic target for antitumor responses. Fc receptors...
10.
Lowe D, Shearer M, Kennedy R
J Cell Biochem
. 2006 Jan;
98(2):235-42.
PMID: 16440328
Vaccination with plasmid DNA is an active area of investigation that is being applied to diseases including cancer and microbial pathogens associated with infectious diseases. Since its discovery, great progress...