Michael Frotscher
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Explore the profile of Michael Frotscher including associated specialties, affiliations and a list of published articles.
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128
Citations
6012
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Recent Articles
1.
Song L, Zhao S, Frotscher M, Chai X
Mol Neurobiol
. 2022 Mar;
59(6):3467-3484.
PMID: 35325397
The adult neocortex is a six-layered structure, consisting of nearly continuous layers of neurons that are generated in a temporally strictly coordinated order. During development, cortical neurons originating from the...
2.
Lee S, Lutz D, Drexler D, Frotscher M, Shen J
PLoS One
. 2020 Oct;
15(10):e0240610.
PMID: 33049001
Presynaptic mitochondrial Ca2+ plays a critical role in the regulation of synaptic transmission and plasticity. The presynaptic bouton of the hippocampal mossy fiber (MF) is much larger in size than...
3.
Lombino F, Muhia M, Lopez-Rojas J, Brill M, Thies E, Ruschkies L, et al.
Sci Rep
. 2019 Nov;
9(1):15940.
PMID: 31685876
Microtubule severing regulates cytoskeletal rearrangement underlying various cellular functions. Katanin, a heterodimer, consisting of catalytic (p60) and regulatory (p80) subunits severs dynamic microtubules to modulate several stages of cell division....
4.
Pahle J, Muhia M, Wagener R, Tippmann A, Bock H, Graw J, et al.
Cereb Cortex
. 2019 Nov;
30(3):1688-1707.
PMID: 31667489
Reelin is an extracellular matrix protein, known for its dual role in neuronal migration during brain development and in synaptic plasticity at adult stages. During the perinatal phase, Reelin expression...
5.
Konietzny A, Gonzalez-Gallego J, Bar J, Perez-Alvarez A, Drakew A, Demmers J, et al.
J Cell Sci
. 2019 Aug;
132(16).
PMID: 31371487
The spine apparatus (SA) is an endoplasmic reticulum-related organelle that is present in a subset of dendritic spines in cortical and pyramidal neurons, and plays an important role in Ca...
6.
Shehabeldin R, Lutz D, Karsak M, Frotscher M, Krieglstein K, Sharaf A
PLoS One
. 2019 Feb;
14(1):e0211849.
PMID: 30703171
[This corrects the article DOI: 10.1371/journal.pone.0200268.].
7.
Shehabeldin R, Lutz D, Karsak M, Frotscher M, Krieglstein K, Sharaf A
PLoS One
. 2018 Jul;
13(7):e0200268.
PMID: 30001399
Serotonin (5-HT) acts as both a morphogenetic factor during early embryonic development and a neuromodulator of circuit plasticity in the mature brain. Dysregulation of serotonin signaling during critical periods is...
8.
Wang S, Brunne B, Zhao S, Chai X, Li J, Lau J, et al.
J Neurosci
. 2017 Nov;
38(1):137-148.
PMID: 29138282
Reelin controls neuronal migration and layer formation. Previous studies in mice deficient in Reelin focused on the result of the developmental process in fixed tissue sections. It has remained unclear...
9.
Lutz D, Sharaf A, Drexler D, Kataria H, Wolters-Eisfeld G, Brunne B, et al.
Sci Rep
. 2017 Nov;
7(1):15268.
PMID: 29127326
The cell adhesion molecule L1 and the extracellular matrix protein Reelin play crucial roles in the developing nervous system. Reelin is known to activate signalling cascades regulating neuronal migration by...
10.
Gowert N, Kruger I, Klier M, Donner L, Kipkeew F, Gliem M, et al.
Cell Signal
. 2017 Sep;
40:210-221.
PMID: 28943410
Reelin is a secreted glycoprotein and essential for brain development and plasticity. Recent studies provide evidence that Reelin modifies platelet actin cytoskeletal dynamics. In this study we sought to dissect...