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Michael F Flessner

Explore the profile of Michael F Flessner including associated specialties, affiliations and a list of published articles. Areas
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Articles 83
Citations 1967
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Recent Articles
11.
Braun W, Abebe K, Brosnahan G, Patterson C, Chapman A, Harris P, et al.
Am J Kidney Dis . 2017 Dec; 71(2):294-296. PMID: 29203126
No abstract available.
12.
Brosnahan G, Abebe K, Rahbari-Oskoui F, Patterson C, Bae K, Schrier R, et al.
Curr Hypertens Rev . 2017 May; 13(2):109-120. PMID: 28460625
Background: Autosomal dominant polycystic kidney disease (ADPKD) commonly results in end-stage renal disease (ESRD), yet a long-term treatment that is well tolerated is still lacking. In a small randomized trial...
13.
Shen C, Landsittel D, Irazabal M, Yu A, Chapman A, Mrug M, et al.
Am J Kidney Dis . 2016 Dec; 69(3):482-484. PMID: 28027795
No abstract available.
14.
Torres V, Abebe K, Schrier R, Perrone R, Chapman A, Yu A, et al.
Kidney Int . 2016 Dec; 91(2):493-500. PMID: 27993381
The CRISP study of polycystic kidney disease (PKD) found that urinary sodium excretion associated with the rate of total kidney volume increase. Whether sodium restriction slows the progression of Autosomal...
15.
Kim Y, Bae S, Cheng T, Tao C, Ge Y, Chapman A, et al.
Phys Med Biol . 2016 Oct; 61(22):7864-7880. PMID: 27779124
Liver and liver cyst volume measurements are important quantitative imaging biomarkers for assessment of disease progression in autosomal dominant polycystic kidney disease (ADPKD) and polycystic liver disease (PLD). To date,...
16.
Moxey-Mims M, Flessner M, Holzman L, Kaskel F, Sedor J, Smoyer W, et al.
Clin J Am Soc Nephrol . 2016 Sep; 11(12):2234-2243. PMID: 27672219
Nephrology has conducted few high-quality clinical trials, and the trials that have been conducted have not resulted in the approval of new treatments for primary or inflammatory glomerular diseases. There...
17.
Kramer H, Stilp A, Laurie C, Reiner A, Lash J, Daviglus M, et al.
J Am Soc Nephrol . 2016 Sep; 28(3):915-922. PMID: 27650483
African ancestry alleles may contribute to CKD among Hispanics/Latinos, but whether associations differ by Hispanic/Latino background remains unknown. We examined the association of CKD measures with African ancestry-specific alleles that...
18.
Mahajan A, Rodan A, Le T, Gaulton K, Haessler J, Stilp A, et al.
Am J Hum Genet . 2016 Sep; 99(3):636-646. PMID: 27588450
We analyzed genome-wide association studies (GWASs), including data from 71,638 individuals from four ancestries, for estimated glomerular filtration rate (eGFR), a measure of kidney function used to define chronic kidney...
19.
Irazabal M, Abebe K, Bae K, Perrone R, Chapman A, Schrier R, et al.
Nephrol Dial Transplant . 2016 Aug; 32(11):1857-1865. PMID: 27484667
Background: Patients with mild autosomal dominant polycystic kidney disease (ADPKD) are less likely to be informative in randomized clinical trials (RCTs). We previously developed an imaging classification of ADPKD (typical...
20.
Dember L, Archdeacon P, Krishnan M, Lacson Jr E, Ling S, Roy-Chaudhury P, et al.
J Am Soc Nephrol . 2016 Jul; 27(10):2955-2963. PMID: 27401689
Pragmatic clinical trials are conducted under the real-world conditions of clinical care delivery. As a result, these trials yield findings that are highly generalizable to the nonresearch setting, identify interventions...