Michael Eby
Overview
Explore the profile of Michael Eby including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
13
Citations
1795
Followers
0
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Recent Articles
11.
Kayagaki N, Phung Q, Chan S, Chaudhari R, Quan C, ORourke K, et al.
Science
. 2007 Nov;
318(5856):1628-32.
PMID: 17991829
Production of type I interferon (IFN-I) is a critical host defense triggered by pattern-recognition receptors (PRRs) of the innate immune system. Deubiquitinating enzyme A (DUBA), an ovarian tumor domain-containing deubiquitinating...
12.
Dornan D, Shimizu H, Mah A, Dudhela T, Eby M, ORourke K, et al.
Science
. 2006 Aug;
313(5790):1122-6.
PMID: 16931761
The ataxia telangiectasia mutated (ATM) protein kinase is a critical component of a DNA-damage response network configured to maintain genomic integrity. The abundance of an essential downstream effecter of this...
13.
Wertz I, ORourke K, Zhou H, Eby M, Aravind L, Seshagiri S, et al.
Nature
. 2004 Jul;
430(7000):694-9.
PMID: 15258597
NF-kappaB transcription factors mediate the effects of pro-inflammatory cytokines such as tumour necrosis factor-alpha and interleukin-1beta. Failure to downregulate NF-kappaB transcriptional activity results in chronic inflammation and cell death, as...
14.
Zhou H, Wertz I, ORourke K, Ultsch M, Seshagiri S, Eby M, et al.
Nature
. 2003 Dec;
427(6970):167-71.
PMID: 14695475
The NF-kappaB family of transcription factors is activated in response to many stimuli, including pro-inflammatory cytokines, environmental stresses and, in the case of B and T lymphocytes, by antigenic stimulation....