Michael E Greenberg
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Explore the profile of Michael E Greenberg including associated specialties, affiliations and a list of published articles.
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158
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23083
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Recent Articles
1.
Traunmuller L, Duffy E, Liu H, Sanalidou S, Assad E, Sun S, et al.
bioRxiv
. 2025 Mar;
PMID: 40060638
The interaction of mammals with a novel environment (NE) results in structural and functional changes in multiple brain areas, including the hippocampus. This experience-dependent circuit reorganization is driven in part...
2.
Nardone C, Gao J, Seo H, Mintseris J, Ort L, Yip M, et al.
bioRxiv
. 2025 Mar;
PMID: 40027645
The midnolin-proteasome pathway degrades many nuclear proteins without ubiquitination, but how it operates mechanistically remains unclear. Here, we present structures of the midnolin-proteasome complex, revealing how established proteasomal components are...
3.
Ivanchenko M, Booth K, Karavitaki K, Antonellis L, Nagy M, Peters C, et al.
bioRxiv
. 2025 Jan;
PMID: 39763983
Mutations in the gene cause the most common form of human hereditary hearing loss, known as DFNB1. is expressed in two cell groups of the cochlea-epithelial cells of the organ...
4.
Nagy M, Price S, Wang K, Gill S, Ren E, Jayne L, et al.
Proc Natl Acad Sci U S A
. 2024 Nov;
121(49):e2418024121.
PMID: 39602276
Spinal motor neuron (MN) dysfunction is the cause of a number of clinically significant movement disorders. Despite the recent approval of gene therapeutics targeting these MN-related disorders, there are no...
5.
Mishra G, Sun E, Chin T, Eckhardt M, Greenberg M, Stroud H
Nat Neurosci
. 2024 Nov;
28(1):62-71.
PMID: 39578572
Mutations in methyl-CpG-binding protein 2 (MeCP2) cause Rett syndrome. MeCP2 is thought to regulate gene transcription by binding to methylated DNA broadly across the genome. Here, using cleavage under target...
6.
Nagy M, Price S, Wang K, Gill S, Ren E, McElrath L, et al.
bioRxiv
. 2024 Sep;
PMID: 39282347
Spinal motor neuron (MN) dysfunction is the cause of a number of clinically significant movement disorders. Despite the recent approval of gene therapeutics targeting these MN-related disorders, there are no...
7.
Griffith E, West A, Greenberg M
Neuron
. 2024 Aug;
112(18):3043-3057.
PMID: 39208805
Neuronal activity-regulated gene expression plays a crucial role in sculpting neural circuits that underpin adaptive brain function. Transcriptional enhancers are now recognized as key components of gene regulation that orchestrate...
8.
Hochbaum D, Hulshof L, Urke A, Wang W, Dubinsky A, Farnsworth H, et al.
Cell
. 2024 Aug;
187(20):5679-5697.e23.
PMID: 39178853
Animals adapt to environmental conditions by modifying the function of their internal organs, including the brain. To be adaptive, alterations in behavior must be coordinated with the functional state of...
9.
Duffy E, Assad E, Kalish B, Greenberg M
Front Mol Neurosci
. 2024 May;
17:1386219.
PMID: 38807924
The mammalian central nervous system coordinates a network of signaling pathways and cellular interactions, which enable a myriad of complex cognitive and physiological functions. While traditional efforts to understand the...
10.
Tzeng C, Whitwam T, Boxer L, Li E, Silberfeld A, Trowbridge S, et al.
Proc Natl Acad Sci U S A
. 2023 Oct;
120(44):e2310344120.
PMID: 37871205
Mutations in give rise to Rett syndrome (RTT), an X-linked neurodevelopmental disorder that results in broad cognitive impairments in females. While the exact etiology of RTT symptoms remains unknown, one...