Michael E Franklin
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Explore the profile of Michael E Franklin including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Sartain F, Viecelli A, Veitch M, Franklin M, Dymock B, Wells J, et al.
Transpl Int
. 2024 Feb;
37:12019.
PMID: 38323070
Solid organ transplant recipients are at an increased risk of developing skin cancers due to chronic immunosuppression, particularly with calcineurin inhibitors. Tacrolimus is the most prescribed calcineurin inhibitor in this...
2.
Jung J, Veitch M, Bridge J, Overgaard N, Cruz J, Linedale R, et al.
Oncoimmunology
. 2018 Sep;
7(9):e1479627.
PMID: 30228949
Patients receiving immunosuppressive drugs to prevent organ transplant rejection exhibit a greatly increased risk of developing cutaneous squamous cell carcinoma (SCC). However, not all immunosuppressive drugs confer the same risk....
3.
Tan T, Crawford D, Franklin M, Jaskowski L, Macdonald G, Jonsson J, et al.
Liver Int
. 2012 Jun;
32(9):1391-9.
PMID: 22676252
Background: Serum hepcidin concentration is potentially affected by inflammation and iron stores in chronic liver disease (CLD), but little is known about the relationship between hepcidin and the degree of...
4.
Taylor P, Franklin M, Tai C, Pillans P
J Chromatogr B Analyt Technol Biomed Life Sci
. 2011 Jul;
883-884:108-12.
PMID: 21727051
Therapeutic drug monitoring of tacrolimus by high-performance liquid chromatography-tandem mass spectrometry has become standard practice. We report on the long-term (4.5 years) use of one such method. Whole blood samples...
5.
Barraclough K, Isbel N, Franklin M, Lee K, Taylor P, Campbell S, et al.
Ther Drug Monit
. 2010 Nov;
32(6):723-33.
PMID: 21068647
Multiple limited sampling strategies (LSSs) have been proposed for estimation of mycophenolic acid (MPA) area under the concentration-time curve from 0 to 12 hours postdose (AUC 0-12) after mycophenolate mofetil...
6.
Measurement of urinary oxypurinol by high performance liquid chromatography-tandem mass spectrometry
Stocker S, Franklin M, Anderson J, Pillans P, Williams K, McLachlan A, et al.
J Chromatogr B Analyt Technol Biomed Life Sci
. 2010 Aug;
878(25):2363-8.
PMID: 20702150
Oxypurinol is the active metabolite of allopurinol which is used to treat hyperuricaemia associated with gout. Both oxypurinol and allopurinol inhibit xanthine oxidase which forms uric acid from xanthine and...
7.
Taylor P, Tai C, Franklin M, Pillans P
Clin Biochem
. 2010 Jul;
44(1):14-20.
PMID: 20599871
Therapeutic drug monitoring of critical dose immunosuppressant drugs is established clinical practice and there are similar good reasons to monitor antiretrovirals. The aim of this article is to review the...
8.
Brown N, Franklin M, Einarsdottir E, Gonde C, Pires M, Taylor P, et al.
Ther Drug Monit
. 2010 Jul;
32(4):420-6.
PMID: 20592649
Mycophenolic acid is now the second most widely used immunosuppressant in solid organ transplantation. Overestimation of mycophenolic acid concentration is a recognized problem of immunoassay, and high-performance liquid chromatography with...
9.
Napoli K, Hammett-Stabler C, Taylor P, Lowe W, Franklin M, Morris M, et al.
Clin Biochem
. 2010 Apr;
43(10-11):910-20.
PMID: 20381483
Objectives: A multi-center evaluation (3 sites) of the LC/MS/MS MassTrak tacrolimus Immunosuppressants Kit (Kit) was undertaken. Design And Methods: Ten aspects of the analytical performance of the Kit were investigated...
10.
Taylor P, Franklin M, Graham K, Pillans P
J Chromatogr B Analyt Technol Biomed Life Sci
. 2006 Nov;
848(2):208-14.
PMID: 17084681
We report here the validation of an HPLC-electrospray-tandem mass spectrometry method for the quantification of everolimus, an immunosuppressant drug. Whole blood samples (100 microl) were extracted by protein precipitation which...