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Michael D Wu

Explore the profile of Michael D Wu including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 415
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Recent Articles
1.
Petersen M, Ryu J, Chang K, Etxeberria A, Bardehle S, Mendiola A, et al.
Neuron . 2017 Nov; 96(5):1003-1012.e7. PMID: 29103804
Blood-brain barrier (BBB) disruption alters the composition of the brain microenvironment by allowing blood proteins into the CNS. However, whether blood-derived molecules serve as extrinsic inhibitors of remyelination is unknown....
2.
Sweet T, Hurley S, Wu M, Olschowka J, Williams J, OBanion M
Radiat Res . 2016 Dec; 186(6):614-623. PMID: 27905869
Understanding the dose-toxicity profile of radiation is critical when evaluating potential health risks associated with natural and man-made sources in our environment. The purpose of this study was to evaluate...
3.
Wu M, Montgomery S, Rivera-Escalera F, Olschowka J, OBanion M
Brain Behav Immun . 2013 Mar; 32:9-18. PMID: 23510988
Alterations in adult hippocampal neurogenesis have been observed in numerous neurological diseases that contain a neuroinflammatory component. Interleukin-1β (IL-1β) is a pro-inflammatory cytokine that contributes to neuroinflammation in many CNS...
4.
Ghosh S, Wu M, Shaftel S, Kyrkanides S, LaFerla F, Olschowka J, et al.
J Neurosci . 2013 Mar; 33(11):5053-64. PMID: 23486975
Neuroinflammation is an important component of Alzheimer's disease (AD) pathogenesis and has been implicated in neurodegeneration. Interleukin-1 (IL-1), a potent inflammatory cytokine in the CNS, is chronically upregulated in human...
5.
Wu M, Hein A, Moravan M, Shaftel S, Olschowka J, OBanion M
Brain Behav Immun . 2011 Oct; 26(2):292-300. PMID: 21983279
Acute neuroinflammation reduces adult hippocampal neurogenesis but the role of chronic neuroinflammation, which may be more representative of ongoing processes in CNS disorders, remains relatively unknown. Interleukin-1β (IL-1β) is a...
6.
Sage B, Wu M, Csink A
Genetics . 2008 Feb; 178(2):749-59. PMID: 18245337
The brown(Dominant) (bw(D)) allele of Drosophila contains a heterochromatic block that causes the locus to interact with centric heterochromatin. This association silences bw(+) in heterozygotes (trans-inactivation) and is dependent on...
7.
Sage B, Jones J, Holmes A, Wu M, Csink A
Mol Cell Biol . 2004 Dec; 25(1):377-88. PMID: 15601858
The brown(Dominant) (bw(D)) allele contains a large insertion of heterochromatin, which causes the locus to aberrantly associate with heterochromatin in interphase nuclei and silences the wild-type allele in heterozygotes. Transgenes...