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Michael D Vahey

Explore the profile of Michael D Vahey including associated specialties, affiliations and a list of published articles. Areas
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Articles 26
Citations 628
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Recent Articles
1.
Kumar J, Xu M, Li Y, You S, Doherty B, Gardiner W, et al.
ACS Sens . 2025 Feb; PMID: 39982783
Airborne transmission via aerosols is a dominant route for the transmission of respiratory pathogens, including avian H5N1 influenza A virus and bacteria. Rapid and direct detection of respiratory pathogen aerosols...
2.
Mitrovich M, Vahey M
ACS Infect Dis . 2025 Jan; 11(1):95-103. PMID: 39743228
RNA viruses possess small genomes encoding a limited repertoire of essential and often multifunctional proteins. Although genetically tagging viral proteins provides a powerful tool for dissecting mechanisms of viral replication...
3.
He Y, Guo Z, Vahey M
bioRxiv . 2024 Nov; PMID: 39605386
During repeated virus exposure, pre-existing antibodies can mask viral epitopes by competing with B cell receptors for antigen. Although this phenomenon has the potential to steer B cell responses away...
4.
Wang S, Gupta R, Benegal A, Avula R, Huang Y, Vahey M, et al.
ACS Sens . 2024 May; 9(6):3096-3104. PMID: 38753414
Lateral flow assays (LFAs) are currently the most popular point-of-care diagnostics, rapidly transforming disease diagnosis from expensive doctor checkups and laboratory-based tests to potential on-the-shelf commodities. Yet, their sensitive element,...
5.
King M, Ruff K, Lin A, Pant A, Farag M, Lalmansingh J, et al.
Cell . 2024 Mar; 187(8):1889-1906.e24. PMID: 38503281
Nucleoli are multicomponent condensates defined by coexisting sub-phases. We identified distinct intrinsically disordered regions (IDRs), including acidic (D/E) tracts and K-blocks interspersed by E-rich regions, as defining features of nucleolar...
6.
He Y, Guo Z, Subiaur S, Benegal A, Vahey M
J Virol . 2024 Jan; 98(2):e0139823. PMID: 38179944
Antibodies are frontline defenders against influenza virus infection, providing protection through multiple complementary mechanisms. Although a subset of monoclonal antibodies (mAbs) has been shown to restrict replication at the level...
7.
Yuanyuan H, Zijian G, Subiaur S, Benegal A, Vahey M
bioRxiv . 2023 Aug; PMID: 37609131
Antibodies are frontline defenders against influenza virus infection, providing protection through multiple complementary mechanisms. Although a subset of monoclonal antibodies (mAbs) have been shown to restrict replication at the level...
8.
Guo Z, He Y, Xu J, Benegal A, Brody S, Vahey M
mBio . 2023 Apr; 14(3):e0359122. PMID: 37078858
Infection of individual cells by multiple virions plays critical roles in the replication and spread of many viruses, but mechanisms that control cellular coinfection during multicycle viral growth remain unclear....
9.
Zhang O, Guo Z, He Y, Wu T, Vahey M, Lew M
Nat Photonics . 2023 Mar; 17(2):179-186. PMID: 36968242
Imaging both the positions and orientations of single fluorophores, termed single-molecule orientation-localisation microscopy, is a powerful tool to study biochemical processes. However, the limited photon budget associated with single-molecule fluorescence...
10.
Kuppan J, Mitrovich M, Vahey M
Elife . 2021 Sep; 10. PMID: 34586067
The complement system is a critical host defense against infection, playing a protective role that can also enhance disease if dysregulated. Although many consequences of complement activation during viral infection...