Michael D Hogarty
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Explore the profile of Michael D Hogarty including associated specialties, affiliations and a list of published articles.
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95
Citations
7217
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Recent Articles
1.
London W, Bousquet H, Irwin M, Hogarty M, Cohn S
Transl Pediatr
. 2024 Nov;
13(10):1899-1901.
PMID: 39524386
No abstract available.
2.
Voeller J, Katzenstein H, Naranjo A, Tenney S, Chen L, London W, et al.
Pediatr Blood Cancer
. 2024 Nov;
72(1):e31407.
PMID: 39502014
Background: Tumor invasion of the spinal canal is detected radiographically in approximately 15% of patients with newly diagnosed neuroblastoma (NB). The optimal clinical approach to maintain excellent survival outcomes while...
3.
Brown E, Adkins E, Mattei P, Hoffer F, Wootton-Gorges S, London W, et al.
J Pediatr Surg
. 2024 Sep;
60(1):161896.
PMID: 39317567
Background: The International Neuroblastoma Risk Group (INRG) classifier utilizes a staging system based on pretreatment imaging criteria in which image-defined risk factors (IDRFs) are used to evaluate the extent of...
4.
Parekh D, Lin H, Batajoo A, Peckham-Gregory E, Karri V, Stanton W, et al.
Br J Haematol
. 2024 Mar;
204(5):1888-1893.
PMID: 38501389
Over 50% of patients with systemic LCH are not cured with front-line therapies, and data to guide salvage options are limited. We describe 58 patients with LCH who were treated...
5.
Cherkaoui S, Yang L, McBride M, Turn C, Lu W, Eigenmann C, et al.
bioRxiv
. 2024 Jan;
PMID: 38260457
Neuroblastoma is a highly lethal childhood tumor derived from differentiation-arrested neural crest cells. Like all cancers, its growth is fueled by metabolites obtained from either circulation or local biosynthesis. Neuroblastomas...
6.
Hogarty M, Ziegler D, Franson A, Chi Y, Tsao-Wei D, Liu K, et al.
Br J Cancer
. 2024 Jan;
130(5):788-797.
PMID: 38200233
Background: MYC genes regulate ornithine decarboxylase (Odc) to increase intratumoral polyamines. We conducted a Phase I trial [NCT02030964] to determine the maximum tolerated dose (MTD) of DFMO, an Odc inhibitor,...
7.
Borankova K, Krchniakova M, Leck L, Kubistova A, Neradil J, Jansson P, et al.
Cell Death Dis
. 2023 Nov;
14(11):747.
PMID: 37973789
Mitochondria are central for cancer responses to therapy-induced stress signals. Refractory tumors often show attenuated sensitivity to apoptotic signaling, yet clinically relevant molecular actors to target mitochondria-mediated resistance remain elusive....
8.
Bender H, Irwin M, Hogarty M, Castleberry R, Maris J, Kao P, et al.
J Clin Oncol
. 2023 Apr;
41(17):3149-3159.
PMID: 37098238
Purpose: In 2006, Children's Oncology Group (COG) reclassified subgroups of toddlers diagnosed with neuroblastoma from high-risk to intermediate-risk, when the age cutoff for high-risk assignment was raised from 365 days...
9.
Pinto N, Naranjo A, Ding X, Zhang F, Hibbitts E, Kennedy R, et al.
Clin Cancer Res
. 2023 Feb;
29(8):1546-1556.
PMID: 36749880
Purpose: Patients ≥18 months of age with International Neuroblastoma Staging System (INSS) stage 3 unfavorable histology (UH), MYCN-nonamplified (MYCN-NA) tumors have favorable survival rates compared with other high-risk neuroblastoma populations....
10.
Coku J, Booth D, Skoda J, Pedrotty M, Vogel J, Liu K, et al.
EMBO J
. 2022 Feb;
41(8):e108272.
PMID: 35211994
Most cancer deaths result from progression of therapy resistant disease, yet our understanding of this phenotype is limited. Cancer therapies generate stress signals that act upon mitochondria to initiate apoptosis....