Michael Cullen
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Explore the profile of Michael Cullen including associated specialties, affiliations and a list of published articles.
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1888
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Recent Articles
11.
Cullen M, Huddart R, Joffe J, Gardiner D, Maynard L, Hutton P, et al.
Eur Urol
. 2020 Jan;
77(3):344-351.
PMID: 31901440
Background: Standard management in the UK for high-risk stage 1 nonseminoma germ cell tumours of the testis (NSGCTT) is two cycles of adjuvant bleomycin, etoposide (360 mg/m), and cisplatin (BEP)...
12.
Wagner S, Roberson D, Boland J, Kreimer A, Yeager M, Cullen M, et al.
J Infect Dis
. 2019 Sep;
220(10):1609-1619.
PMID: 31536132
Background: Human papillomaviruses (HPV) cause over 500 000 cervical cancers each year, most of which occur in low-resource settings. Human papillomavirus genotyping is important to study natural history and vaccine...
13.
Wagner S, Roberson D, Boland J, Yeager M, Cullen M, Mirabello L, et al.
J Clin Microbiol
. 2019 Mar;
57(5).
PMID: 30814267
We have developed a new human papillomavirus (HPV) genotyping assay for detection of 51 HPV genotypes by next-generation sequencing (NGS). The TypeSeq assay consists of 3 PCR steps that equalize...
14.
Clifford G, Tenet V, Georges D, Alemany L, Pavon M, Chen Z, et al.
Papillomavirus Res
. 2019 Feb;
7:67-74.
PMID: 30738204
Background: Human papillomavirus (HPV)16 can be separated into genetic sub-lineages (A1-4, B1-4, C1-4, D1-4) which may have differential cervical cancer risk. Methods: A next-generation sequencing assay was used to whole-genome...
15.
Mirabello L, Clarke M, Nelson C, Dean M, Wentzensen N, Yeager M, et al.
Viruses
. 2018 Feb;
10(2).
PMID: 29438321
Of the ~60 human papillomavirus (HPV) genotypes that infect the cervicovaginal epithelium, only 12-13 "high-risk" types are well-established as causing cervical cancer, with HPV16 accounting for over half of all...
16.
Mirabello L, Yeager M, Yu K, Clifford G, Xiao Y, Zhu B, et al.
Cell
. 2017 Sep;
170(6):1164-1174.e6.
PMID: 28886384
Although most cervical human papillomavirus type 16 (HPV16) infections become undetectable within 1-2 years, persistent HPV16 causes half of all cervical cancers. We used a novel HPV whole-genome sequencing technique...
17.
Seckl M, Ottensmeier C, Cullen M, Schmid P, Ngai Y, Muthukumar D, et al.
J Clin Oncol
. 2017 Feb;
35(14):1506-1514.
PMID: 28240967
Purpose Treating small-cell lung cancer (SCLC) remains a therapeutic challenge. Experimental studies show that statins exert additive effects with agents, such as cisplatin, to impair tumor growth, and observational studies...
18.
Makowsky R, Lhaki P, Wiener H, Bhatta M, Cullen M, Johnson D, et al.
Infect Genet Evol
. 2016 Nov;
46:7-11.
PMID: 27725301
Objectives/background: Sequence variants in HPV16 confer differences in oncogenic potential; however, to date there have not been any HPV sequence studies performed in Nepal. The objective of this study was...
19.
Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome
Machiela M, Zhou W, Karlins E, Sampson J, Freedman N, Yang Q, et al.
Nat Commun
. 2016 Jun;
7:11843.
PMID: 27291797
To investigate large structural clonal mosaicism of chromosome X, we analysed the SNP microarray intensity data of 38,303 women from cancer genome-wide association studies (20,878 cases and 17,425 controls) and...
20.
Mirabello L, Yeager M, Cullen M, Boland J, Chen Z, Wentzensen N, et al.
J Natl Cancer Inst
. 2016 May;
108(9).
PMID: 27130930
Background: HPV16 is a common sexually transmitted infection although few infections lead to cervical precancer/cancer; we cannot distinguish nor mechanistically explain why only certain infections progress. HPV16 can be classified...