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Michael Chrisofos

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Recent Articles
1.
Kaltsas A, Giannakodimos I, Markou E, Adamos K, Stavropoulos M, Kratiras Z, et al.
Microorganisms . 2025 Feb; 13(2). PMID: 40005617
Erectile dysfunction (ED) is a prevalent male sexual disorder characterized by the persistent inability to achieve or maintain an erection sufficient for satisfactory sexual performance. While its etiology is multifactorial,...
2.
Kaltsas A, Giannakas T, Stavropoulos M, Kratiras Z, Chrisofos M
Diseases . 2025 Feb; 13(2). PMID: 39997060
Background/objectives: Benign prostatic hyperplasia (BPH) is among the most common conditions affecting men as they age, resulting in lower urinary tract symptoms (LUTS) that can profoundly impact quality of life....
3.
Giannakodimos I, Kaltsas A, Moulavasilis N, Kratiras Z, Mitropoulos D, Chrisofos M, et al.
J Clin Med . 2025 Jan; 14(2). PMID: 39860459
: Multiparametric-Magnetic Resonance Imaging(mp-MRI) presents the ability to detect clinically significant cancer, aiming to avoid biopsy if the results are negative or target an abnormal lesion if a suspected lesion...
4.
Kaltsas A, Markou E, Kyrgiafini M, Zikopoulos A, Symeonidis E, Dimitriadis F, et al.
Genes (Basel) . 2025 Jan; 16(1). PMID: 39858640
Male reproductive health is governed by an intricate interplay of genetic, epigenetic, and environmental factors. Epigenetic mechanisms-encompassing DNA methylation, histone modifications, and non-coding RNA activity-are crucial both for spermatogenesis and...
5.
Kaltsas A, Dimitriadis F, Zachariou A, Sofikitis N, Chrisofos M
Cells . 2025 Jan; 14(2). PMID: 39851548
Phosphodiesterases, particularly the type 5 isoform (PDE5), have gained recognition as pivotal regulators of male reproductive physiology, exerting significant influence on testicular function, sperm maturation, and overall fertility potential. Over...
6.
Kaltsas A, Dimitriadis F, Chrisofos M, Sofikitis N, Zachariou A
Medicina (Kaunas) . 2025 Jan; 60(12. PMID: 39768935
Varicocele repair in men with non-obstructive azoospermia (NOA) remains a subject of debate due to inconsistent outcomes. This study aimed to evaluate the impact of microsurgical varicocelectomy on sperm recovery...
7.
Kaltsas A, Zikopoulos A, Kojovic V, Dimitriadis F, Sofikitis N, Chrisofos M, et al.
Medicina (Kaunas) . 2025 Jan; 60(12. PMID: 39768802
: Recurrent pregnancy loss (RPL) affects numerous couples worldwide and has traditionally been attributed mainly to maternal factors. However, recent evidence highlights significant paternal influences on pregnancy viability and outcomes....
8.
Kaltsas A, Stavros S, Kratiras Z, Zikopoulos A, Machairiotis N, Potiris A, et al.
Biomedicines . 2025 Jan; 12(12. PMID: 39767586
: Non-obstructive azoospermia (NOA) is a severe form of male infertility characterized by the absence of sperm in the ejaculate due to impaired spermatogenesis. Testicular sperm extraction (TESE) combined with...
9.
Kaltsas A, Zikopoulos A, Markou E, Zachariou A, Stavropoulos M, Kratiras Z, et al.
J Clin Med . 2024 Dec; 13(23). PMID: 39685846
Varicoceles are a common contributor to male infertility, significantly impacting male-factor infertility cases. Traditional diagnostic methods often lack the sensitivity to detect the molecular and cellular disruptions caused by varicoceles,...
10.
Kaltsas A, Chrisofos M, Symeonidis E, Zachariou A, Stavropoulos M, Kratiras Z, et al.
Cancers (Basel) . 2024 Oct; 16(20). PMID: 39456547
Background/objectives: Prostate cancer (PCa) is a significant global health issue. The relationship between alcohol consumption and PCa risk has been the subject of extensive research, yet findings remain inconsistent. This...