Michael C Carroll
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Explore the profile of Michael C Carroll including associated specialties, affiliations and a list of published articles.
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134
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Recent Articles
1.
Zhu D, Castrillon C, Carroll M
Immunol Rev
. 2025 Feb;
330(1):e70005.
PMID: 39917856
The immune system relies on carefully calibrated cellular machineries to enable distinction between endogenous and foreign molecules, with autoimmunity arising when this balance is disrupted. As potent autoantibody factories, B...
2.
van den Broek T, Oleinika K, Rahmayanti S, Castrillon C, van der Poel C, Carroll M
Sci Immunol
. 2024 Mar;
9(93):eadi8150.
PMID: 38517953
In autoreactive germinal centers (GC) initiated by a single rogue B cell clone, wild-type B cells expand and give rise to clones that target other autoantigens, known as epitope spreading....
3.
Akama-Garren E, Yin X, Prestwood T, Ma M, Utz P, Carroll M
Sci Immunol
. 2024 Feb;
9(92):eadj7029.
PMID: 38363829
T cell help is a crucial component of the normal humoral immune response, yet whether it promotes or restrains autoreactive B cell responses remains unclear. Here, we observe that autoreactive...
4.
Zhu D, Maurer D, Castrillon C, Deng Y, Nait Mohamed F, Ma M, et al.
bioRxiv
. 2024 Jan;
PMID: 38260501
In systemic lupus erythematosus, recent findings highlight the extrafollicular (EF) pathway as prominent origin of autoantibody-secreting cells (ASCs). CD21CD11c B cells, associated with aging, infection, and autoimmunity, are contributors to...
5.
Aw E, Zhang Y, Yalcin E, Herrmann U, Lin S, Langston K, et al.
Brain Behav Immun
. 2023 Dec;
116:419.
PMID: 38065810
No abstract available.
6.
Fahlquist-Hagert C, Wittenborn T, Terczynska-Dyla E, Kastberg K, Yang E, Rallistan A, et al.
Nat Commun
. 2023 Nov;
14(1):6941.
PMID: 37907556
Circumstantial evidence suggests that B cells may instruct T cells to break tolerance. Here, to test this hypothesis, we used a murine model in which a single B cell clone...
7.
Aw E, Zhang Y, Yalcin E, Herrmann U, Lin S, Langston K, et al.
Brain Behav Immun
. 2023 Jun;
114:511-522.
PMID: 37369340
Among systemic lupus erythematosus (SLE) patients, neuropsychiatric symptoms are highly prevalent, being observed in up to 80% of adult and 95% of pediatric patients. Type 1 interferons, particularly interferon alpha...
8.
Castrillon C, Simoni L, van den Broek T, van der Poel C, Akama-Garren E, Ma M, et al.
Elife
. 2023 Jun;
12.
PMID: 37341394
Affinity matured self-reactive antibodies are found in autoimmune diseases like systemic lupus erythematous. Here, we used fate-mapping reporter mice and single-cell transcriptomics coupled to antibody repertoire analysis to characterize the...
9.
Aw E, Lin S, Zhang Y, Herrmann U, Yalcin E, Langston K, et al.
bioRxiv
. 2023 May;
PMID: 37131759
bioRxiv has withdrawn this manuscript because it was posted without the consent of all authors. If you have any questions, please contact the corresponding author.
10.
Akama-Garren E, Carroll M
Scand J Immunol
. 2022 May;
95(6):e13192.
PMID: 35587582
The germinal center serves as a site of B cell selection and affinity maturation, critical processes for productive adaptive immunity. In autoimmune disease tolerance is broken in the germinal center...