Michael B Sharpe
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Explore the profile of Michael B Sharpe including associated specialties, affiliations and a list of published articles.
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47
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1690
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Recent Articles
1.
Battista J, Clark B, Patterson M, Beaulieu L, Sharpe M, Schreiner L, et al.
J Appl Clin Med Phys
. 2018 Sep;
13(2):146-147.
PMID: 30252921
No abstract available.
2.
Goli A, Boutilier J, Craig T, Sharpe M, Chan T
Phys Med Biol
. 2018 Jul;
63(19):195004.
PMID: 29998853
Current practice for treatment planning optimization can be both inefficient and time consuming. In this paper, we propose an automated planning methodology that aims to combine both explorative and prescriptive...
3.
Babier A, Boutilier J, Sharpe M, McNiven A, Chan T
Phys Med Biol
. 2018 Apr;
63(10):105004.
PMID: 29633957
We developed and evaluated a novel inverse optimization (IO) model to estimate objective function weights from clinical dose-volume histograms (DVHs). These weights were used to solve a treatment planning problem...
4.
Moxon-Emre I, Bouffet E, Taylor M, Laperriere N, Sharpe M, Laughlin S, et al.
J Neurosurg Pediatr
. 2016 Mar;
18(1):29-40.
PMID: 27015518
OBJECTIVE Craniospinal irradiation damages the white matter in children treated for medulloblastoma, but the treatment-intensity effects are unclear. In a cross-sectional retrospective study, the effects of treatment with the least...
5.
Boutilier J, Craig T, Sharpe M, Chan T
Med Phys
. 2016 Mar;
43(3):1212-21.
PMID: 26936706
Purpose: To determine how training set size affects the accuracy of knowledge-based treatment planning (KBP) models. Methods: The authors selected four models from three classes of KBP approaches, corresponding to...
6.
Boutilier J, Lee T, Craig T, Sharpe M, Chan T
Med Phys
. 2015 Apr;
42(4):1586-95.
PMID: 25832049
Purpose: To develop and evaluate the clinical applicability of advanced machine learning models that simultaneously predict multiple optimization objective function weights from patient geometry for intensity-modulated radiation therapy of prostate...
7.
Sharpe M, Moore K, Orton C
Med Phys
. 2014 Dec;
41(12):120601.
PMID: 25471945
No abstract available.
8.
Manem V, Kohandel M, Hodgson D, Sharpe M, Sivaloganathan S
Int J Radiat Biol
. 2014 Oct;
91(3):209-17.
PMID: 25356906
Unlabelled: Abstract Purpose: Numerous studies have implicated elevated second cancer risks as a result of radiation therapy. Our aim in this paper was to contribute to an understanding of the...
9.
Purdie T, Dinniwell R, Fyles A, Sharpe M
Int J Radiat Oncol Biol Phys
. 2014 Aug;
90(3):688-95.
PMID: 25160607
Purpose: To demonstrate the large-scale clinical implementation and performance of an automated treatment planning methodology for tangential breast intensity modulated radiation therapy (IMRT). Methods And Materials: Automated planning was used...
10.
Lee T, Hammad M, Chan T, Craig T, Sharpe M
Med Phys
. 2013 Dec;
40(12):121706.
PMID: 24320492
Purpose: Intensity-modulated radiation therapy (IMRT) treatment planning typically combines multiple criteria into a single objective function by taking a weighted sum. The authors propose a statistical model that predicts objective...