Michael A Simpson
Overview
Explore the profile of Michael A Simpson including associated specialties, affiliations and a list of published articles.
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150
Citations
5801
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Recent Articles
1.
Dand N, Stuart P, Bowes J, Ellinghaus D, Nititham J, Saklatvala J, et al.
Nat Commun
. 2025 Feb;
16(1):2051.
PMID: 40021644
Psoriasis is a common, debilitating immune-mediated skin disease. Genetic studies have identified biological mechanisms of psoriasis risk, including those targeted by effective therapies. However, the genetic liability to psoriasis is...
2.
Schwarz C, Blegvad C, Baudry D, Tosi I, Lee S, Chung R, et al.
J Invest Dermatol
. 2025 Feb;
PMID: 39983980
No abstract available.
3.
Rayinda T, Dand N, McSweeney S, Christou E, Ung C, Stefanato C, et al.
JAMA Dermatol
. 2025 Feb;
PMID: 39937552
Importance: Frontal fibrosing alopecia (FFA) is an inflammatory and scarring form of hair loss of increasing prevalence that most commonly affects women. An improved understanding of the genetic basis of...
4.
GWAS Meta-Analysis Identifies Susceptibility Loci for Keloids and Hypertrophic Scarring in Europeans
Dand N, Ung C, Saklatvala J, Simpson M, Barker J, Shaw T, et al.
J Invest Dermatol
. 2025 Jan;
PMID: 39746571
No abstract available.
5.
Ramessur R, Saklatvala J, Budu-Aggrey A, Ostaszewski M, Mobus L, Greco D, et al.
JAMA Cardiol
. 2024 Sep;
9(11):1009-1017.
PMID: 39292496
Importance: The epidemiological link between immune-mediated diseases (IMIDs) and cardiovascular disease has often been attributed to systemic inflammation. However, the direction of causality and the biological mechanisms linking cardiovascular disease...
6.
Rayinda T, McSweeney S, Christou E, Ung C, Fenton D, McGrath J, et al.
JAMA Dermatol
. 2024 May;
160(7):732-735.
PMID: 38809548
Importance: Frontal fibrosing alopecia (FFA) is an increasingly prevalent form of follicular lichen planus, causing irreversible hair loss predominantly in postmenopausal individuals. An earlier genome-wide meta-analysis of female FFA identified...
7.
Dand N, Stuart P, Bowes J, Ellinghaus D, Nititham J, Saklatvala J, et al.
medRxiv
. 2023 Oct;
PMID: 37873414
Psoriasis is a common, debilitating immune-mediated skin disease. Genetic studies have identified biological mechanisms of psoriasis risk, including those targeted by effective therapies. However, the genetic liability to psoriasis is...
8.
Saklatvala J, Hanscombe K, Mahil S, Tsoi L, Elder J, Barker J, et al.
J Invest Dermatol
. 2023 Mar;
143(8):1598-1601.e10.
PMID: 36870556
No abstract available.
9.
Tsakok T, Saklatvala J, Rispens T, Loeff F, de Vries A, Allen M, et al.
JCI Insight
. 2023 Feb;
8(4).
PMID: 36810251
Targeted biologic therapies can elicit an undesirable host immune response characterized by the development of antidrug antibodies (ADA), an important cause of treatment failure. The most widely used biologic across...
10.
Grange L, Reynolds J, Ullah F, Isidor B, Shearer R, Latypova X, et al.
Nat Commun
. 2022 Nov;
13(1):6664.
PMID: 36333305
Embryonic development is dictated by tight regulation of DNA replication, cell division and differentiation. Mutations in DNA repair and replication genes disrupt this equilibrium, giving rise to neurodevelopmental disease characterized...