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Michael A McNutt

Explore the profile of Michael A McNutt including associated specialties, affiliations and a list of published articles. Areas
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Articles 83
Citations 2520
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Recent Articles
1.
Yu D, Sun Y, McNutt M, Xu S
Front Surg . 2022 May; 9:853363. PMID: 35548181
Objectives: The prognosis for stage I pulmonary adenocarcinoma is generally good. However, some patients with stage I pulmonary adenocarcinoma have an unexpectedly poor outcome. This warrants consideration of adjunct markers....
2.
Lu D, Liu L, Sun Y, Song J, Yin Q, Zhang G, et al.
Nat Immunol . 2020 Jan; 21(3):287-297. PMID: 31932812
Cancer cells subvert immune surveillance through inhibition of T cell effector function. Elucidation of the mechanism of T cell dysfunction is therefore central to cancer immunotherapy. Here, we report that...
3.
Yuan Y, Zhao X, Wang P, Mei F, Zhou J, Jin Y, et al.
FASEB J . 2019 Jul; 33(10):11148-11162. PMID: 31291551
Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) α is the first identified isoform of the well-known tumor suppressor PTEN. PTENα has an evolutionarily conserved 173-aa N terminus compared...
4.
Li Y, Jin Y, Liu B, Lu D, Zhu M, Jin Y, et al.
Blood . 2019 Mar; 133(19):2079-2089. PMID: 30926592
Neutrophils are a major component of immune defense and are recruited through neutrophil chemotaxis in response to invading pathogens. However, the molecular mechanism that controls neutrophil chemotaxis remains unclear. Here,...
5.
Feng J, Dang Y, Zhang W, Zhao X, Zhang C, Hou Z, et al.
Proc Natl Acad Sci U S A . 2019 Mar; 116(14):6868-6877. PMID: 30886105
Arginine methylation is a ubiquitous posttranslational modification that regulates critical cellular processes including signal transduction and pre-mRNA splicing. Here, we report that the tumor-suppressor PTEN is methylated by protein arginine...
6.
Qi H, Ning X, Yu C, Ji X, Jin Y, McNutt M, et al.
Cell Death Dis . 2019 Feb; 10(3):170. PMID: 30787272
Tumor growth and progression is characteristically associated with the synergistic effects of uncontrolled cellular proliferation and cell survival under stress. Pyruvate kinase M2 (PKM2) contributes to both of these effects....
7.
Lu D, Song J, Sun Y, Qi F, Liu L, Jin Y, et al.
J Autoimmun . 2018 Aug; 94:156-165. PMID: 30100102
Dysregulation of innate immunity accompanied by excessive interferon production contributes to autoimmune disease. However, the mechanism by which the immune response is modulated in autoimmune disorders is largely unknown. Here...
8.
Li G, Yang J, Yang C, Zhu M, Jin Y, McNutt M, et al.
Autophagy . 2018 Jul; 14(10):1742-1760. PMID: 29969932
Abbreviations: BECN1 beclin 1; CCCP carbonyl cyanide m-chlorophenylhydrazone; FBXO7 F-box protein 7; FS fraction shortening; HSPA1L heat shock protein family A (Hsp70) member 1 like; HW: BW heart weight:body weight...
9.
Liu Y, Zhao Q, Yin Y, McNutt M, Zhang T, Cao Y
Biochem Biophys Res Commun . 2018 Feb; 497(3):897-902. PMID: 29476737
Acute gouty arthritis (AGA) is one of the most common forms of auto-inflammatory arthritis. IL-17 is a key proinflammatory cytokine which has been implicated in several autoimmune diseases. However, to...
10.
Liu Y, Du X, Zhang S, Liu Y, Zhang Q, Yin Q, et al.
Oncotarget . 2017 Dec; 8(58):98040-98050. PMID: 29228672
The spindle assembly checkpoint (SAC) restrains anaphase progression to ensure all chromosomes attach properly to the spindle. Although SAC timing has been extensively investigated in mitosis, its mechanism of regulation...