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Michael A Cahill

Explore the profile of Michael A Cahill including associated specialties, affiliations and a list of published articles. Areas
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Articles 42
Citations 773
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Recent Articles
1.
Thejer B, Infantino V, Santarsiero A, Pappalardo I, Abatematteo F, Teakel S, et al.
Int J Mol Sci . 2023 Apr; 24(7). PMID: 37047353
Sigma-2 receptor (S2R) is a S2R ligand-binding site historically associated with reportedly 21.5 kDa proteins that have been linked to several diseases, such as cancer, Alzheimer's disease, and schizophrenia. The...
2.
Cahill M
Front Biosci (Landmark Ed) . 2022 Dec; 27(11):318. PMID: 36472116
The title usage of Latin 'where are you going' extends the question from where 'did you come?' posed in the accompanying paper and extends consideration of how ancient eukaryotic and...
3.
Cahill M
Front Biosci (Landmark Ed) . 2022 Dec; 27(11):317. PMID: 36472108
The title usage of 'from where have you come' is from a now dead language (Latin) that foundationally influenced modern English (not the major influence, but an essential formative one)....
4.
Teakel S, Marama M, Aragao D, Tsimbalyuk S, Mackie E, Soares da Costa T, et al.
FEBS Lett . 2022 Aug; 596(18):2409-2417. PMID: 35993565
We recently reported that the membrane-associated progesterone receptor (MAPR) protein family (mammalian members: PGRMC1, PGRMC2, NEUFC and NENF) originated from a new class of prokaryotic cytochrome b (cytb ) domain...
5.
Bai Y, Ludescher M, Poschmann G, Stuhler K, Wyrich M, Oles J, et al.
Cancers (Basel) . 2021 Nov; 13(22). PMID: 34830790
In previous studies, we reported that progesterone receptor membrane component 1 (PGRMC1) is implicated in progestin signaling and possibly associated with increased breast cancer risk upon combined hormone replacement therapy....
6.
Cahill M, Neubauer H
Cancers (Basel) . 2021 Feb; 13(3). PMID: 33572771
This is a preface by the guest editors of the special issue of featuring the biology of progesterone (P4) receptor membrane component (PGRMC) proteins as it relates to metabolism and...
7.
Izzo N, Colom-Cadena M, Riad A, Xu J, Singh M, Abate C, et al.
eNeuro . 2020 Oct; 7(6). PMID: 33028631
The σ-2 receptor (S2R) complex has been implicated in CNS disorders ranging from anxiety and depression to neurodegenerative disorders such as Alzheimer's disease (AD). The proteins comprising the S2R complex...
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Thejer B, Adhikary P, Teakel S, Fang J, Weston P, Gurusinghe S, et al.
BMC Mol Cell Biol . 2020 Apr; 21(1):26. PMID: 32293262
Background: Progesterone receptor membrane component 1 (PGRMC1) is often elevated in cancers, and exists in alternative states of phosphorylation. A motif centered on PGRMC1 Y180 was evolutionarily acquired concurrently with...
10.
Hehenberger E, Eitel M, Fortunato S, Miller D, Keeling P, Cahill M
Mol Phylogenet Evol . 2020 Apr; 148:106814. PMID: 32278076
The membrane-associated progesterone receptor (MAPR) family consists of heme-binding proteins containing a cytochrome b (cytb) domain characterized by the presence of a MAPR-specific interhelical insert region (MIHIR) between helices 3...