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Mian Horvath

Explore the profile of Mian Horvath including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 46
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Recent Articles
1.
Horvath M, Yang R, Castaneda D, Callender M, Aiken E, Voigt A, et al.
BMC Biol . 2025 Jan; 23(1):28. PMID: 39875977
Background: The microbiome regulates the respiratory epithelium's immunomodulatory functions. To explore how the microbiome's biodiversity affects microbe-epithelial interactions, we screened 58 phylogenetically diverse microbes for their transcriptomic effect on human...
2.
Balana A, Mahul-Mellier A, Nguyen B, Horvath M, Javed A, Hard E, et al.
Nat Chem Biol . 2024 Feb; 20(5):656. PMID: 38413747
No abstract available.
3.
Balana A, Mahul-Mellier A, Nguyen B, Horvath M, Javed A, Hard E, et al.
Nat Chem Biol . 2024 Feb; 20(5):646-655. PMID: 38347213
Amyloid-forming proteins such α-synuclein and tau, which are implicated in Alzheimer's and Parkinson's disease, can form different fibril structures or strains with distinct toxic properties, seeding activities and pathology. Understanding...
4.
Derman I, Yeo M, Castaneda D, Callender M, Horvath M, Mo Z, et al.
Biofabrication . 2023 Aug; 15(4). PMID: 37536321
Progenitor human nasal epithelial cells (hNECs) are an essential cell source for the reconstruction of the respiratory pseudostratified columnar epithelium composed of multiple cell types in the context of infection...
5.
Derman I, Yeo M, Castaneda D, Callender M, Horvath M, Mo Z, et al.
bioRxiv . 2023 Apr; PMID: 37034627
Human nasal epithelial cells (hNECs) are an essential cell source for the reconstruction of the respiratory pseudostratified columnar epithelium composed of multiple cell types in the context of infection studies...
6.
Balana A, Mahul-Mellier A, Nguyen B, Horvath M, Javed A, Hard E, et al.
bioRxiv . 2023 Mar; PMID: 36945566
The process of amyloid fibril formation remains one of the primary targets for developing diagnostics and treatments for several neurodegenerative diseases (NDDs). Amyloid-forming proteins such α-Synuclein and Tau, which are...
7.
Braun A, Liao E, Horvath M, Kalra P, Acosta K, Young M, et al.
NPJ Parkinsons Dis . 2021 Jun; 7(1):52. PMID: 34183676
We have developed a high-throughput drug discovery platform, measuring fluorescence resonance energy transfer (FRET) with fluorescent alpha-synuclein (αSN) biosensors, to detect spontaneous pre-fibrillar oligomers in living cells. Our two αSN...
8.
Caputo A, Liang Y, Raabe T, Lo A, Horvath M, Zhang B, et al.
eNeuro . 2020 Aug; 7(4). PMID: 32788297
α-Synuclein (aSyn) participates in synaptic vesicle trafficking and synaptic transmission but its misfolding is also strongly implicated in Parkinson's disease (PD) and other neurodegenerative synucleinopathies in which misfolded aSyn accumulates...