Meytal Galilee
Overview
Explore the profile of Meytal Galilee including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
39
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Recent Articles
1.
Li H, Wu S, Lin R, Xiao Y, Morotti A, Wang Y, et al.
Mol Plant
. 2023 Jan;
16(3):549-570.
PMID: 36639870
The presence of anticancer clerodane diterpenoids is a chemotaxonomic marker for the traditional Chinese medicinal plant Scutellaria barbata, although the molecular mechanisms behind clerodane biosynthesis are unknown. Here, we report...
2.
Galilee M, Alian A
PLoS Pathog
. 2018 Jan;
14(1):e1006849.
PMID: 29364950
Reverse transcriptase (RT) is the target for the majority of anti-HIV-1 drugs. As with all anti-AIDS treatments, continued success of RT inhibitors is persistently disrupted by the occurrence of resistance...
3.
Galilee M, Britan-Rosich E, Griner S, Uysal S, Baumgartel V, Lamb D, et al.
Structure
. 2016 Oct;
24(11):1936-1946.
PMID: 27692964
HIV-1 integrase (IN) catalyzes viral DNA integration into the host genome and facilitates multifunctional steps including virus particle maturation. Competency of IN to form multimeric assemblies is functionally critical, presenting...
4.
Khwaja A, Galilee M, Marx A, Alian A
Sci Rep
. 2016 Apr;
6:24957.
PMID: 27102180
Viruses use a strategy of high mutational rates to adapt to environmental and therapeutic pressures, circumventing the deleterious effects of random single-point mutations by coevolved compensatory mutations, which restore protein...
5.
Marx A, Galilee M, Alian A
Sci Rep
. 2015 Dec;
5:18191.
PMID: 26678087
The strong association of APOBEC3 cytidine deaminases with somatic mutations leading to cancers accentuates the importance of their tight intracellular regulation to minimize cellular transformations. We reveal a novel allosteric...
6.
Galilee M, Alian A
Structure
. 2014 Sep;
22(10):1512-9.
PMID: 25199694
Retroviral DNA integration into the host genome is mediated by nucleoprotein assemblies containing tetramers of viral integrase (IN). Whereas the fully active form of IN comprises a dimer of dimers,...