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Meshell D Johnson

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Articles 8
Citations 381
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Recent Articles
1.
Wong M, Johnson M
PLoS One . 2013 Feb; 8(1):e55545. PMID: 23383221
The alveolar epithelium serves as a barrier between organism and environment and functions as the first line of protection against potential respiratory pathogens. Alveolar type II (TII) cells have traditionally...
2.
Wong M, Chapin O, Johnson M
Am J Respir Cell Mol Biol . 2011 Dec; 46(5):641-50. PMID: 22205632
The alveolar epithelium serves as a barrier to the entry of potential respiratory pathogens. Alveolar Type II (TII) cells have immunomodulatory functions, but whether Type I (TI) cells, which comprise...
3.
Dobbs L, Johnson M, Vanderbilt J, Allen L, Gonzalez R
Cell Physiol Biochem . 2010 Jan; 25(1):55-62. PMID: 20054144
Pulmonary alveolar type I cells (TI cell) are very large (approximately 5400 microm(2) in surface area) squamous cells that cover more than 98% of the internal surface area of rodent...
4.
Dobbs L, Johnson M
Respir Physiol Neurobiol . 2007 Aug; 159(3):283-300. PMID: 17689299
The alveolar surface comprises >99% of the internal surface area of the lungs. At birth, the fetal lung rapidly converts from a state of net fluid secretion, which is necessary...
5.
Factor P, Mutlu G, Chen L, Mohameed J, Akhmedov A, Meng F, et al.
Proc Natl Acad Sci U S A . 2007 Mar; 104(10):4083-8. PMID: 17360481
Adenosine is a purine nucleoside that regulates cell function through G protein-coupled receptors that activate or inhibit adenylyl cyclase. Based on the understanding that cAMP regulates alveolar epithelial active Na(+)...
6.
Johnson M
Mol Biosyst . 2007 Feb; 3(3):178-86. PMID: 17308664
This highlight article summarizes the current published literature of ion channels and ion transport in type I cells. Twenty years ago, the general theory of ion and fluid transport in...
7.
Johnson M, Bao H, Helms M, Chen X, Tigue Z, Jain L, et al.
Proc Natl Acad Sci U S A . 2006 Mar; 103(13):4964-9. PMID: 16549766
Efficient gas exchange in the lungs depends on regulation of the amount of fluid in the thin (average 0.2 mum) liquid layer lining the alveolar epithelium. Fluid fluxes are regulated...
8.
Johnson M, Widdicombe J, Allen L, Barbry P, Dobbs L
Proc Natl Acad Sci U S A . 2002 Feb; 99(4):1966-71. PMID: 11842214
Transport of lung liquid is essential for both normal pulmonary physiologic processes and for resolution of pathologic processes. The large internal surface area of the lung is lined by alveolar...