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Merlin Nanayakkara

Explore the profile of Merlin Nanayakkara including associated specialties, affiliations and a list of published articles. Areas
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Articles 32
Citations 621
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Recent Articles
1.
Bellomo C, Furone F, Rotondo R, Ciscognetti I, Carpinelli M, Nicoletti M, et al.
Cells . 2024 Dec; 13(23). PMID: 39682729
Protein tyrosine phosphatases (PTPs) are a family of enzymes essential for numerous cellular processes, such as cell growth, inflammation, differentiation, immune-mediated responses and oncogenic transformation. The aim of this review...
2.
Furone F, Bellomo C, Carpinelli M, Nicoletti M, Hewa-Munasinghege F, Mordaa M, et al.
Front Med (Lausanne) . 2023 May; 10:1085578. PMID: 37215707
Celiac disease (CD) is an autoimmune enteropathy caused by an abnormal immune response to gliadin peptides in genetically predisposed individuals. For people with CD, the only available therapy thus far...
3.
Sposito S, Secondo A, Romanelli A, Montefusco A, Nanayakkara M, Auricchio S, et al.
Int J Mol Sci . 2023 Jan; 24(2). PMID: 36675008
Celiac disease (CD) is an inflammatory intestinal disease caused by the ingestion of gluten-containing cereals by genetically predisposed individuals. Constitutive differences between cells from CD patients and control subjects, including...
4.
Nanayakkara M, Bellomo C, Furone F, Maglio M, Marano A, Lania G, et al.
Cells . 2023 Jan; 12(1). PMID: 36611909
Background & Aims: Celiac disease (CeD) is an immune-mediated enteropathy triggered in genetically susceptible (HLA-DQ2/8) individuals by a group of wheat proteins and related prolamins from cereals. The celiac intestine...
5.
Barone M, Auricchio R, Nanayakkara M, Greco L, Troncone R, Auricchio S
Int J Mol Sci . 2022 Jul; 23(13). PMID: 35806180
Celiac disease (CD) is an immune-mediated enteropathy triggered in genetically susceptible individuals by gluten-containing cereals. A central role in the pathogenesis of CD is played by the HLA-restricted gliadin-specific intestinal...
6.
Conte M, Nigro F, Porpora M, Bellomo C, Furone F, Budelli A, et al.
Int J Mol Sci . 2022 Apr; 23(7). PMID: 35409015
Celiac disease (CD) is an autoimmune disease characterized by an altered immune response stimulated by gliadin peptides that are not digested and cause damage to the intestinal mucosa. The aim...
7.
Porpora M, Conte M, Lania G, Bellomo C, Rapacciuolo L, Chirdo F, et al.
Int J Mol Sci . 2022 Feb; 23(4). PMID: 35216089
Celiac disease (CD) is a chronic inflammatory disease caused by a genetic predisposition to an abnormal T cell-mediated immune response to the gluten in the diet. Different environmental proinflammatory factors...
8.
Poeta M, Cioffi V, Buccigrossi V, Nanayakkara M, Baggieri M, Peltrini R, et al.
Sci Rep . 2021 Nov; 11(1):21725. PMID: 34741071
SARS-CoV-2 enters the intestine by the spike protein binding to angiotensin-converting enzyme 2 (ACE2) receptors in enterocyte apical membranes, leading to diarrhea in some patients. Early treatment of COVID-19-associated diarrhea...
9.
Discepolo V, Lania G, Ten Eikelder M, Nanayakkara M, Sepe L, Tufano R, et al.
Int J Mol Sci . 2021 Apr; 22(5). PMID: 33800150
Celiac disease (CD) is a frequent intestinal inflammatory disease occurring in genetically susceptible individuals upon gluten ingestion. Recent studies point to a role in CD for genes involved in cell...
10.
Falcigno L, Calvanese L, Conte M, Nanayakkara M, Barone M, DAuria G
Int J Mol Sci . 2020 Dec; 21(23). PMID: 33291297
Gluten fragments released in gut of celiac individuals activate the innate or adaptive immune systems. The molecular mechanisms associated with the adaptive response involve a series of immunodominant gluten peptides...