Merja Blauer
Overview
Explore the profile of Merja Blauer including associated specialties, affiliations and a list of published articles.
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22
Citations
343
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Recent Articles
1.
Natkin R, Pennanen P, Syvala H, Blauer M, Kesseli J, Tammela T, et al.
PLoS One
. 2023 Feb;
18(2):e0281645.
PMID: 36809527
Androgen deprivation therapy is the cornerstone treatment of advanced prostate cancer. Eventually prostate cancer cells overcome androgen deprivation therapy, giving rise to castration resistant prostate cancer (CRPC) characterized by increased...
2.
Blauer M, Sand J, Laukkarinen J
Pancreatology
. 2021 Jan;
21(2):384-389.
PMID: 33454208
Background/objectives: Acute pancreatitis develops as an inflammatory response to pancreatic tissue injury. Postoperative pancreatitis has recently been associated with increased occurrence of complications. Activation of the mitogen-activated protein kinase p38...
3.
Blauer M, Laaninen M, Sand J, Laukkarinen J
Pancreatology
. 2019 Feb;
19(2):252-257.
PMID: 30792046
Background/objectives: Wnt/β-catenin signalling plays vital roles in tissue homeostasis. Dysregulation of the pathway has been implicated in the pathogenesis of cancer and fibroses in numerous tissues, including the pancreas. We...
4.
Syvala H, Pennanen P, Blauer M, Tammela T, Murtola T
Biochem Biophys Res Commun
. 2016 Nov;
481(1-2):46-50.
PMID: 27833018
We evaluated the effects of simvastatin and antiandrogen enzalutamide on growth and androgen signaling in androgen-sensitive LNCaP and VCaP prostate cancer cells. Simvastatin alone abolished androgen-induced growth in both cell...
5.
Pennanen P, Syvala H, Blauer M, Savinainen K, Ylikomi T, Tammela T, et al.
Eur J Pharmacol
. 2016 Jun;
788:160-167.
PMID: 27341997
The anti-diabetic drug metformin and cholesterol-lowering statins inhibit prostate cancer cell growth in vitro and have been linked with lowered risk of prostate cancer in epidemiological studies. We evaluated the...
6.
Blauer M, Laaninen M, Sand J, Laukkarinen J
Pancreatology
. 2016 Apr;
16(4):570-7.
PMID: 27075041
Background/objectives: Pancreatic stellate cells (PSCs) are the key fibrogenic cells in the pancreas. Acinar cell injury is known to trigger PSC activation. To facilitate the experimental analysis of the crosstalk...
7.
Blauer M, Sand J, Laukkarinen J
Pancreatology
. 2015 May;
15(4):366-71.
PMID: 26005021
Background/objectives: Vitamin D is an antiproliferative and differentiation-promoting secosteroid hormone with pleiotropic homeostatic functions in bone and extraskeletal tissues. Signaling of vitamin D is mediated via its ubiquitously expressed nuclear...
8.
Laaninen M, Blauer M, Sand J, Nordback I, Laukkarinen J
Gastroenterol Res Pract
. 2014 Aug;
2014:460363.
PMID: 25147563
Objectives. Previously we have shown that a pancreas with over 40% acinar cells is exposed to postoperative pancreatitis and other complications after pancreaticoduodenectomy (PD). Our aim was to analyze the...
9.
Blauer M, Sand J, Nordback I, Laukkarinen J
Pancreas
. 2014 Jun;
43(5):762-7.
PMID: 24927222
Objectives: Because of rapid loss of functional differentiation that regularly occurs in vitro, culture systems permitting long-term studies on pancreatic acinar cells pose a major technical challenge. We recently described...
10.
Hashimoto D, Blauer M, Hirota M, Ikonen N, Sand J, Laukkarinen J
Eur J Cancer
. 2014 Feb;
50(7):1382-90.
PMID: 24503026
Background And Aim: Autophagy is a regulated process of degradation and recycling of cellular constituents. The role of autophagy in pancreatic cancer is still not clear. Some studies indicate that...