Merel Rijnsburger
Overview
Explore the profile of Merel Rijnsburger including associated specialties, affiliations and a list of published articles.
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11
Citations
106
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Recent Articles
1.
Alsema A, Wijering M, Miedema A, Kotah J, Koster M, Rijnsburger M, et al.
Nat Neurosci
. 2024 Nov;
27(12):2341-2353.
PMID: 39501035
Multiple sclerosis (MS) is an inflammatory disease of the central nervous system characterized by myelin loss and progressive neurodegeneration. To understand MS lesion initiation and progression, we generate spatial gene...
2.
Broos J, van der Burgt R, Konings J, Rijnsburger M, Werz O, de Vries H, et al.
J Neuroinflammation
. 2024 Jan;
21(1):21.
PMID: 38233951
Background: Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system (CNS), characterized by neuroinflammation, demyelination, and neurodegeneration. Considering the increasing prevalence among young adults worldwide and...
3.
Diepenbroek C, Rijnsburger M, van Irsen A, Eggels L, Kisner A, Foppen E, et al.
Metabolism
. 2023 Oct;
150:155696.
PMID: 37804881
Background: Growing evidence demonstrates the role of the striatal dopamine system in the regulation of glucose metabolism. Treatment with dopamine antagonists is associated with insulin resistance and hyperglycemia, while dopamine...
4.
Loonstra F, Falize K, de Ruiter L, Schoonheim M, Strijbis E, Killestein J, et al.
J Neurol
. 2022 Dec;
270(4):2018-2030.
PMID: 36562851
Background: An imbalance of adipokines, hormones secreted by white adipose tissue, is suggested to play a role in the immunopathology of multiple sclerosis (MS). In people with MS (PwMS) of...
5.
Rijnsburger M, Djuric N, Mulder I, de Vries H
Int J Mol Sci
. 2021 Oct;
22(19).
PMID: 34639186
Multiple sclerosis (MS), a chronic inflammatory and demyelinating disease of the central nervous system (CNS), is a major clinical and societal problem, which has a tremendous impact on the life...
6.
Rodriguez-Lorenzo S, Ferreira Francisco D, Vos R, van Het Hof B, Rijnsburger M, Schroten H, et al.
Acta Neuropathol Commun
. 2020 Mar;
8(1):35.
PMID: 32192527
The choroid plexus (CP) is a key regulator of the central nervous system (CNS) homeostasis through its secretory, immunological and barrier properties. Accumulating evidence suggests that the CP plays a...
7.
Kamermans A, Verhoeven T, van Het Hof B, Koning J, Borghuis L, Witte M, et al.
Front Immunol
. 2019 Oct;
10:2312.
PMID: 31636637
To date, available treatment strategies for multiple sclerosis (MS) are ineffective in preventing or reversing progressive neurologic deterioration, creating a high, and unmet medical need. One potential way to fight...
8.
Kamermans A, Rijnsburger M, Chakraborty A, van der Pol S, de Vries H, van Horssen J
Front Immunol
. 2019 May;
10:950.
PMID: 31130950
Multiple sclerosis (MS) is a chronic inflammatory disorder of the central nervous system (CNS) characterized by the presence of focal demyelinated plaques. Sufficient clearance of myelin and cellular debris is...
9.
Belegri E, Rijnsburger M, Eggels L, Unmehopa U, Scheper W, Boelen A, et al.
Front Neurosci
. 2017 May;
11:270.
PMID: 28555094
Protein-folding stress at the Endoplasmic Reticulum (ER) occurs in the hypothalamus during diet-induced obesity (DIO) and is linked to metabolic disease development. ER stress is buffered by the activation of...
10.
Rijnsburger M, Belegri E, Eggels L, Unmehopa U, Boelen A, Serlie M, et al.
Physiol Behav
. 2016 Apr;
162:61-8.
PMID: 27083123
The hypothalamus plays a fundamental role in regulating homeostatic processes including regulation of food intake. Food intake is driven in part by energy balance, which is sensed by specific brain...