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Meredyth G Ll Wilkinson

Explore the profile of Meredyth G Ll Wilkinson including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Sherman M, Nicolai R, Datyner E, Rosina S, Hamilton A, Ardalan K, et al.
Rheumatology (Oxford) . 2025 Feb; PMID: 39928372
Objectives: Janus kinase inhibition (JAKi) has been proposed as a treatment for idiopathic inflammatory myopathies to target increased interferon signalling. Predominantly retrospective reports have demonstrated effectiveness of JAKi in refractory...
2.
Radziszewska A, Peckham H, Restuadi R, Kartawinata M, Moulding D, de Gruijter N, et al.
Clin Exp Immunol . 2024 Dec; 219(1). PMID: 39719886
Juvenile systemic lupus erythematosus (JSLE) is an autoimmune condition which causes significant morbidity in children and young adults and is more severe in its presentation than adult-onset SLE. While many...
3.
Papadopoulou C, Chew C, Wilkinson M, McCann L, Wedderburn L
Nat Rev Rheumatol . 2023 May; 19(6):343-362. PMID: 37188756
The childhood-onset or juvenile idiopathic inflammatory myopathies (JIIMs) are a heterogenous group of rare and serious autoimmune diseases of children and young people that predominantly affect the muscles and skin...
4.
Wilkinson M, Moulding D, McDonnell T, Orford M, Wincup C, Ting J, et al.
Ann Rheum Dis . 2022 Dec; 82(5):658-669. PMID: 36564154
Objectives: To define the host mechanisms contributing to the pathological interferon (IFN) type 1 signature in Juvenile dermatomyositis (JDM). Methods: RNA-sequencing was performed on CD4, CD8, CD14 and CD19 cells...
5.
McCann L, Livermore P, Wilkinson M, Wedderburn L
Clin Exp Rheumatol . 2022 Feb; 40(2):394-403. PMID: 35225221
Juvenile onset idiopathic inflammatory myopathy (IIM) has many similarities and distinct differences from adult-onset disease. This review will focus on recent developments in understanding and treatment of juvenile dermatomyositis (JDM),...
6.
Robinson G, Wilkinson M, Wincup C
Front Immunol . 2022 Feb; 12:806560. PMID: 35154082
Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder in which pathogenic abnormalities within both the innate and adaptive immune response have been described. In order to activated, proliferate and...
7.
Deakin C, Bowes J, Rider L, Miller F, Pachman L, Sanner H, et al.
Hum Mol Genet . 2022 Jan; 31(14):2471-2481. PMID: 35094092
Juvenile dermatomyositis (JDM) is a rare, severe autoimmune disease and the most common idiopathic inflammatory myopathy of children. JDM and adult-onset dermatomyositis (DM) have similar clinical, biological and serological features,...
8.
Wilkinson M, Deakin C, Papadopoulou C, Eleftheriou D, Wedderburn L
Pediatr Rheumatol Online J . 2021 Sep; 19(1):146. PMID: 34563217
Juvenile Idiopathic Inflammatory Myopathies (IIM) are a group of rare diseases that are heterogeneous in terms of pathology that can include proximal muscle weakness, associated skin changes and systemic involvement....
9.
Wilkinson M, Radziszewska A, Wincup C, Ioannou Y, Isenberg D, Manson J, et al.
Rheumatology (Oxford) . 2019 Jul; 59(1):194-204. PMID: 31292651
Objective: The inflammatory idiopathic myopathies (IIM) are a group of rare autoimmune diseases defined by muscle weakness and characterized by pro-inflammatory infiltrates in muscle. Little is known about the immunological...
10.
Wilkinson M, Rosser E
Front Immunol . 2019 Mar; 10:214. PMID: 30837988
B cells carry out a central role in the pathogenesis of autoimmune disease. In addition to the production of autoantibodies, B cells can contribute to disease development by presenting autoantigens...