Mengxuan Chen
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Explore the profile of Mengxuan Chen including associated specialties, affiliations and a list of published articles.
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22
Citations
143
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Recent Articles
1.
Chen B, Chen M, Chang M, Ge Y, Gunning W, Assaly R, et al.
Kidney Int
. 2025 Jan;
PMID: 39862971
Melanocortin therapeutics, exemplified by adrenocorticotropic hormone, have a proven steroidogenic-independent anti-proteinuric and glomerular protective effect. The biological functions of melanocortins are mediated by melanocortin receptors (MCR), including MC1R, which recent...
2.
Li M, Chen M, Li H, Gao D, Zhao L, Zhu M
Front Cell Dev Biol
. 2025 Jan;
12():1510897.
PMID: 39830208
The main characteristics of Parkinson's disease (PD) are the loss of dopaminergic (DA) neurons and abnormal aggregation of cytosolic proteins. However, the exact pathogenesis of PD remains unclear, with ferroptosis...
3.
Gibberellin-Induced Transcription Factor MYB71 Negatively Regulates Salvianolic Acid Biosynthesis in
Han C, Dong X, Xing X, Wang Y, Feng X, Sang W, et al.
Molecules
. 2025 Jan;
29(24.
PMID: 39769982
, the valuable traditional Chinese medicinal plant, has been used in clinics for thousands of years. The water-soluble salvianolic acid compounds are bioactive substances used in treating many diseases. Gibberellins...
4.
Yuan L, Pan L, Wang Y, Zhao J, Fang L, Zhou Y, et al.
Cell Discov
. 2024 Nov;
10(1):117.
PMID: 39587089
As a critical component of the tumour immune microenvironment (TIME), the resident microbiota promotes tumorigenesis across a variety of cancer types. Here, we integrated multiple types of omics data, including...
5.
Yu L, He K, Wu Y, Hao K, Wang Y, Yao J, et al.
BMC Biotechnol
. 2024 Nov;
24(1):94.
PMID: 39563265
Background: Dendrobium catenatum is a perennial herb of the genus Dendrobium orchidaceae. It has been known as "Golden Grass, Soft Gold" since ancient times with effects of strengthening the body,...
6.
Ding M, Zheng L, Hua X, Chen M, Zhong Q, Huang T, et al.
Talanta
. 2024 Oct;
283:127109.
PMID: 39481347
Developing efficient and comprehensive analysis methods for metabolomics and lipidomics in the biological tissues and body fluids is essential for understanding the disease mechanisms. Although various two-dimensional liquid chromatography-mass spectrometry...
7.
Gong A, Qiao Y, Chen M, Alam Z, Malhotra D, Dworkin L, et al.
Front Pharmacol
. 2024 Sep;
15:1462936.
PMID: 39309006
Ethyl carbamate (EC) is a process contaminant found in fermented foods and alcoholic beverages. Metabolic conversion of ethyl carbamate generates vinyl carbamate (VC), a carcinogenic metabolite. EC, as a Group...
8.
Chen M, Fang Y, Ge Y, Qiu S, Dworkin L, Gong R
Redox Biol
. 2024 Mar;
72:103127.
PMID: 38527400
Emerging evidence suggests that GSK3β, a redox-sensitive transducer downstream of insulin signaling, acts as a convergent point for myriad pathways implicated in kidney injury, repair, and regeneration. However, its role...
9.
Li Z, Chen M, Wang W, Liu Q, Li N, He B, et al.
Zhong Nan Da Xue Xue Bao Yi Xue Ban
. 2022 Nov;
47(9):1191-1199.
PMID: 36411702
Objectives: Methotrexate (MTX) is the most common therapeutic agent that may have the risk of drug-induced liver injury. Its pathogenic mechanism is related to oxidative stress caused by mitochondrial dysfunction....
10.
Ma J, Liu Q, Chen M, He B, Li Y, Zhang M, et al.
J Physiol Biochem
. 2022 Sep;
78(4):885-895.
PMID: 36138295
Activated hepatic stellate cells (HSCs) are considered the major drivers in the process of hepatic fibrosis. This study intends to explore the mechanism underlying microRNA (miR)-34b-5p effects over liver fibrosis...