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Melissa Vitela

Explore the profile of Melissa Vitela including associated specialties, affiliations and a list of published articles. Areas
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Citations 97
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Recent Articles
1.
Bowman M, Gomez J, Mitchell N, Wells A, Vitela M, Clarke K, et al.
Cells . 2022 Aug; 11(15). PMID: 35954298
Selective serotonin reuptake inhibitors (SSRIs) are less efficacious in treating depression in children than in adults. SSRIs block serotonin uptake via the high-affinity, low-capacity serotonin transporter. However, the low-affinity, high-capacity...
2.
Bowman M, Vitela M, Clarke K, Koek W, Daws L
Int J Mol Sci . 2020 Oct; 21(20). PMID: 33066466
Major depressive disorder is typically treated with selective serotonin reuptake inhibitors (SSRIs), however, SSRIs take approximately six weeks to produce therapeutic effects, if any. Not surprisingly, there has been great...
3.
Gilman T, Owens W, George C, Metzel L, Vitela M, Ferreira L, et al.
J Pharmacol Exp Ther . 2019 Sep; 371(2):268-277. PMID: 31481515
Eating disorders such as anorexia typically emerge during adolescence, are characterized by engagement in compulsive and detrimental behaviors, and are often comorbid with neuropsychiatric disorders and drug abuse. No effective...
4.
Gilman T, George C, Vitela M, Herrera-Rosales M, Basiouny M, Koek W, et al.
Eur J Neurosci . 2018 May; PMID: 29797618
Originally, uptake-mediated termination of monoamine (e.g., serotonin and dopamine) signalling was believed to only occur via high-affinity, low-capacity transporters ("uptake ") such as the serotonin or dopamine transporters, respectively. Now,...
5.
Horton R, Apple D, Owens W, Baganz N, Cano S, Mitchell N, et al.
J Neurosci . 2013 Jun; 33(25):10534-43. PMID: 23785165
Mood disorders cause much suffering and lost productivity worldwide, compounded by the fact that many patients are not effectively treated by currently available medications. The most commonly prescribed antidepressant drugs...
6.
Carolina Rodrigues Dias A, Vitela M, Colombari E, Mifflin S
Am J Physiol Heart Circ Physiol . 2004 Dec; 288(1):H256-62. PMID: 15598868
The neuromodulatory effect of NO on glutamatergic transmission has been studied in several brain areas. Our previous single-cell studies suggested that NO facilitates glutamatergic transmission in the nucleus of the...