Melissa A Willman
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Explore the profile of Melissa A Willman including associated specialties, affiliations and a list of published articles.
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11
Citations
245
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Recent Articles
1.
Anwar I, Berman D, DeLaura I, Gao Q, Willman M, Miller A, et al.
Sci Transl Med
. 2023 Aug;
15(711):eadf6376.
PMID: 37647390
Prior studies of anti-CD40 ligand (CD40L)-based immunosuppression demonstrated effective prevention of islet and kidney allograft rejection in nonhuman primate models; however, clinical development was halted because of thromboembolic complications. An...
2.
Paez-Mayorga J, Campa-Carranza J, Capuani S, Hernandez N, Liu H, Chua C, et al.
Nat Commun
. 2022 Dec;
13(1):7951.
PMID: 36572684
Pancreatic islet transplantation efficacy for type 1 diabetes (T1D) management is limited by hypoxia-related graft attrition and need for systemic immunosuppression. To overcome these challenges, we developed the Neovascularized Implantable...
3.
Perucca Orfei C, Bowles A, Kouroupis D, Willman M, Ragni E, Kaplan L, et al.
Front Bioeng Biotechnol
. 2021 Oct;
9:711964.
PMID: 34616717
Our understanding of tendon biology continues to evolve, thus leading to opportunities for developing novel, evidence-based effective therapies for the treatment of tendon disorders. Implementing the knowledge of tendon stem/progenitor...
4.
Kenyon N, Willman M, Han D, Leeman R, Rabassa A, Diaz W, et al.
Am J Transplant
. 2021 May;
21(11):3524-3537.
PMID: 34008325
Mesenchymal stem cells (MSC) have been shown to be immunomodulatory, tissue regenerative, and graft promoting; however, several questions remain with regard to ideal MSC source and timing of administration. In...
5.
Kouroupis D, Willman M, Best T, Kaplan L, Correa D
Stem Cell Res Ther
. 2021 May;
12(1):282.
PMID: 33971950
No abstract available.
6.
Kouroupis D, Willman M, Best T, Kaplan L, Correa D
Stem Cell Res Ther
. 2021 Jan;
12(1):44.
PMID: 33413649
Background: To investigate the in vitro and in vivo anti-inflammatory/anti-fibrotic capacity of IFP-MSC manufactured as 3D spheroids. Our hypothesis is that IFP-MSC do not require prior cell priming to acquire...
7.
Bowles A, Kouroupis D, Willman M, Perucca Orfei C, Agarwal A, Correa D
Stem Cells
. 2020 May;
38(8):1034-1049.
PMID: 32379908
CD146 bone marrow-derived mesenchymal stem/stromal cells (BM-MSCs) play key roles in the perivascular niche, skeletogenesis, and hematopoietic support; however, comprehensive evaluation of therapeutic potency has yet to be determined. In...
8.
Stabler C, Giraldo J, Berman D, Gattas-Asfura K, Willman M, Rabassa A, et al.
Am J Transplant
. 2019 Oct;
20(3):689-700.
PMID: 31597005
Islet cell transplantation can lead to insulin independence, reduced hypoglycemia, and amelioration of diabetes complications in patients with type 1 diabetes. The systemic delivery of anti-inflammatory agents, while considered crucial...
9.
Kouroupis D, Bowles A, Willman M, Perucca Orfei C, Colombini A, Best T, et al.
Sci Rep
. 2019 Jul;
9(1):10864.
PMID: 31350444
The infrapatellar fat pad (IFP) serves as a reservoir of Mesenchymal Stem Cells (MSC), and with adjacent synovium plays key roles in joint disease including the production of Substance P...
10.
Berman D, Willman M, Han D, Kleiner G, Kenyon N, Cabrera O, et al.
Diabetes
. 2010 Jul;
59(10):2558-68.
PMID: 20622174
Objective: To test the graft-promoting effects of mesenchymal stem cells (MSCs) in a cynomolgus monkey model of islet/bone marrow transplantation. Research Design And Methods: Cynomolgus MSCs were obtained from iliac...