Melinda Zana
Overview
Explore the profile of Melinda Zana including associated specialties, affiliations and a list of published articles.
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19
Citations
135
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Recent Articles
1.
Szeky B, Jurakova V, Fouskova E, Feher A, Zana M, Karl V, et al.
PLoS One
. 2024 Dec;
19(12):e0313514.
PMID: 39630626
Astrocytes are specialized glial cell types of the central nervous system (CNS) with remarkably high abundance, morphological and functional diversity. Astrocytes maintain neural metabolic support, synapse regulation, blood-brain barrier integrity...
2.
Balogh A, Bodi-Jakus M, Karl V, Bellak T, Szeky B, Farkas J, et al.
Sci Rep
. 2024 Sep;
14(1):22572.
PMID: 39343771
In the present study, we aimed to establish and characterize a mature cortical spheroid model system for Kleefstra syndrome (KS) using patient-derived iPSC. We identified key differences in the growth...
3.
Jurakova V, Szeky B, Zapletalova M, Feher A, Zana M, Pandey S, et al.
Biol Proced Online
. 2024 Sep;
26(1):30.
PMID: 39342077
Background: Astrocytes have recently gained attention as key players in the pathogenesis of neurodegenerative diseases, including Alzheimer's disease. Numerous differentiation protocols have been developed to study human astrocytes in vitro....
4.
Kistamas K, Lamberto F, Vaiciuleviciute R, Leal F, Muenthaisong S, Marte L, et al.
Int J Mol Sci
. 2024 Sep;
25(17).
PMID: 39273136
One of the many unresolved obstacles in the field of cardiovascular research is an uncompromising in vitro cardiac model. While primary cell sources from animal models offer both advantages and...
5.
Chandrasekaran V, Wellens S, Bourguignon A, Djidrovski I, Fransen L, Ghosh S, et al.
Toxicol In Vitro
. 2024 Apr;
98:105826.
PMID: 38615723
Human induced pluripotent stem cells (iPSC) have the potential to produce desired target cell types in vitro and allow for the high-throughput screening of drugs/chemicals at population level thereby minimising...
6.
Horanszky A, Shashikadze B, Elkhateib R, Lombardo S, Lamberto F, Zana M, et al.
Front Cell Dev Biol
. 2023 Sep;
11:1236243.
PMID: 37664457
Bisphenol A (BPA) exposure is associated with a plethora of neurodevelopmental abnormalities and brain disorders. Previous studies have demonstrated BPA-induced perturbations to critical neural stem cell (NSC) characteristics, such as...
7.
Lamberto F, Shashikadze B, Elkhateib R, Lombardo S, Horanszky A, Balogh A, et al.
Environ Pollut
. 2023 Aug;
335:122359.
PMID: 37567409
Early embryonic development represents a sensitive time-window during which the foetus might be vulnerable to the exposure of environmental contaminants, potentially leading to heart diseases also later in life. Bisphenol...
8.
Capinha L, Zhang Y, Holzer A, Uckert A, Zana M, Carta G, et al.
Arch Toxicol
. 2022 Dec;
97(2):523-545.
PMID: 36576512
Environmental or occupational exposure of humans to trichloroethylene (TCE) has been associated with different extrahepatic toxic effects, including nephrotoxicity and neurotoxicity. Bioactivation of TCE via the glutathione (GSH) conjugation pathway...
9.
Nunes C, Singh P, Mazidi Z, Murphy C, Bourguignon A, Wellens S, et al.
Toxicol In Vitro
. 2022 Feb;
81:105333.
PMID: 35182771
Most OECD guidelines for chemical risk assessment include tests performed on animals, raising financial, ethical and scientific concerns. Thus, the development of human-based models for toxicity testing is highly encouraged....
10.
Mitrecic D, Hribljan V, Jagecic D, Isakovic J, Lamberto F, Horanszky A, et al.
Int J Mol Sci
. 2022 Jan;
23(2).
PMID: 35055039
From the first success in cultivation of cells in vitro, it became clear that developing cell and/or tissue specific cultures would open a myriad of new opportunities for medical research....