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Melih Sener

Explore the profile of Melih Sener including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 377
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Recent Articles
1.
Chan A, Tajkhorshid E, Luthey-Schulten Z, Sener M
J Phys Chem B . 2024 Dec; 129(1):52-70. PMID: 39723618
Diffusion of mobile charge carriers, such as ferredoxin and plastocyanin, often constitutes a rate-determining step in photosynthetic energy conversion. The diffusion time scales typically exceed that of other primary bioenergetic...
2.
Pirnia A, Maqdisi R, Mittal S, Sener M, Singharoy A
J Phys Chem B . 2024 Apr; 128(14):3302-3319. PMID: 38562105
Bioenergetic processes in cells, such as photosynthesis or respiration, integrate many time and length scales, which makes the simulation of energy conversion with a mere single level of theory impossible....
3.
Sener M, Levy S, Stone J, Christensen A, Isralewitz B, Patterson R, et al.
Parallel Comput . 2021 Nov; 102. PMID: 34824485
Conversion of sunlight into chemical energy, namely photosynthesis, is the primary energy source of life on Earth. A visualization depicting this process, based on multiscale computational models from electronic to...
4.
Singharoy A, Maffeo C, Delgado-Magnero K, Swainsbury D, Sener M, Kleinekathofer U, et al.
Cell . 2019 Nov; 179(5):1098-1111.e23. PMID: 31730852
We report a 100-million atom-scale model of an entire cell organelle, a photosynthetic chromatophore vesicle from a purple bacterium, that reveals the cascade of energy conversion steps culminating in the...
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MacGregor-Chatwin C, Sener M, Barnett S, Hitchcock A, Barnhart-Dailey M, Maghlaoui K, et al.
Plant Cell . 2017 Apr; 29(5):1119-1136. PMID: 28364021
Photosystem I (PSI) is the dominant photosystem in cyanobacteria and it plays a pivotal role in cyanobacterial metabolism. Despite its biological importance, the native organization of PSI in cyanobacterial thylakoid...
7.
Hitchcock A, Hunter C, Sener M
J Phys Chem B . 2017 Mar; 121(15):3787-3797. PMID: 28301162
Cell doubling times of the purple bacterium Rhodobacter sphaeroides during photosynthetic growth are determined experimentally and computationally as a function of illumination. For this purpose, energy conversion processes in an...
8.
Sener M, Strumpfer J, Singharoy A, Hunter C, Schulten K
Elife . 2016 Aug; 5. PMID: 27564854
The chromatophore of purple bacteria is an intracellular spherical vesicle that exists in numerous copies in the cell and that efficiently converts sunlight into ATP synthesis, operating typically under low...
9.
Stone J, Sener M, Vandivort K, Barragan A, Singharoy A, Teo I, et al.
Parallel Comput . 2016 Jun; 55:17-27. PMID: 27274603
The cellular process responsible for providing energy for most life on Earth, namely photosynthetic light-harvesting, requires the cooperation of hundreds of proteins across an organelle, involving length and time scales...
10.
Chandler D, Strumpfer J, Sener M, Scheuring S, Schulten K
Biophys J . 2014 Jun; 106(11):2503-10. PMID: 24896130
Purple photosynthetic bacteria harvest light using pigment-protein complexes which are often arranged in pseudo-organelles called chromatophores. A model of a chromatophore from Rhodospirillum photometricum was constructed based on atomic force...