Melanie Lagarrigue
Overview
Explore the profile of Melanie Lagarrigue including associated specialties, affiliations and a list of published articles.
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20
Citations
219
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Recent Articles
1.
Merdas M, Lagarrigue M, Umbdenstock T, Lhumeau A, Dartiguelongue F, Vanbellingen Q, et al.
Anal Chem
. 2021 Sep;
93(39):13242-13250.
PMID: 34546718
During drug development, detailed investigations of the pharmacokinetic profile of the drug are required to characterize its absorption, distribution, metabolism, and excretion properties. Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging...
2.
Merdas M, Lagarrigue M, Vanbellingen Q, Umbdenstock T, Da Violante G, Pineau C
J Mass Spectrom
. 2021 Jun;
56(10):e4731.
PMID: 34080257
Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI MSI) is a key tool for the analysis of biological tissues. It provides spatial and quantitative information about different types of analytes within...
3.
Simoes Eugenio M, Faurez F, Kara-Ali G, Lagarrigue M, Uhart P, Bonnet M, et al.
Front Mol Biosci
. 2021 May;
8:645134.
PMID: 33937329
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a well-known apoptosis inducer and a potential anticancer agent. When caspases and inhibitors of apoptosis proteins (IAPs) are inhibited, TRAIL induces necroptosis. Molecular...
4.
Lagarrigue M, Lavigne R, Guevel B, Palmer A, Rondel K, Guillot L, et al.
J Mass Spectrom
. 2020 Oct;
55(12):e4633.
PMID: 33043525
Spermatozoa acquire their fertilizing capacity during a complex maturation process that occurs in the epididymis. This process involves a substantial molecular remodeling at the surface of the gamete. Epididymis is...
5.
Mias-Lucquin D, Dos Santos Morais R, Cheron A, Lagarrigue M, Winder S, Chenuel T, et al.
J Struct Biol
. 2019 Nov;
209(1):107411.
PMID: 31689503
Dystrophin is a large intracellular protein that prevents sarcolemmal ruptures by providing a mechanical link between the intracellular actin cytoskeleton and the transmembrane dystroglycan complex. Dystrophin deficiency leads to the...
6.
Dos Santos Morais R, Delalande O, Perez J, Mias-Lucquin D, Lagarrigue M, Martel A, et al.
Biophys J
. 2018 Sep;
115(7):1231-1239.
PMID: 30197181
Scaffolding proteins play important roles in supporting the plasma membrane (sarcolemma) of muscle cells. Among them, dystrophin strengthens the sarcolemma through protein-lipid interactions, and its absence due to gene mutations...
7.
Melaine N, Com E, Bellaud P, Guillot L, Lagarrigue M, Morrice N, et al.
J Proteome Res
. 2018 Aug;
17(12):4197-4210.
PMID: 30130116
For the C-HPP consortium, dark proteins include not only uPE1, but also missing proteins (MPs, PE2-4), smORFs, proteins from lncRNAs, and products from uncharacterized transcripts. Here, we investigated the expression...
8.
Lardenois A, Jagot S, Lagarrigue M, Guevel B, Ledevin M, Larcher T, et al.
Proteomics
. 2016 Jun;
16(14):2028-42.
PMID: 27246553
Proteomic profiling plays a decisive role in the elucidation of molecular signatures representative of a specific clinical context. MuStem cell based therapy represents a promising approach for clinical applications to...
9.
Lagarrigue M, Caprioli R, Pineau C
J Proteomics
. 2016 May;
144:133-9.
PMID: 27178109
Risk assessment related to the exposure of humans to chemicals released into the environment is a major concern of our modern societies. In this context, toxicology plays a crucial role...
10.
Jumeau F, Com E, Lane L, Duek P, Lagarrigue M, Lavigne R, et al.
J Proteome Res
. 2015 Jul;
14(9):3606-20.
PMID: 26168773
The Chromosome-Centric Human Proteome Project (C-HPP) aims at cataloguing the proteins as gene products encoded by the human genome in a chromosome-centric manner. The existence of products of about 82%...