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Melanie J Stables

Explore the profile of Melanie J Stables including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Stables M, Shah S, Camon E, Lovering R, Newson J, Bystrom J, et al.
Blood . 2011 Oct; 118(26):e192-208. PMID: 22012065
Macrophages are either classically (M1) or alternatively-activated (M2). Whereas this nomenclature was generated from monocyte-derived macrophages treated in vitro with defined cytokine stimuli, the phenotype of in vivo-derived macrophages is...
2.
Scotland R, Stables M, Madalli S, Watson P, Gilroy D
Blood . 2011 Sep; 118(22):5918-27. PMID: 21911834
Females are protected against mortality arising from severe sepsis; however, the precise mechanisms that confer this survival advantage in females over males are unclear. Resident leukocytes in resting tissues have...
3.
Stables M, Gilroy D
Prog Lipid Res . 2010 Jul; 50(1):35-51. PMID: 20655950
Originally regarded as just membrane constituents and energy storing molecules, lipids are now recognised as potent signalling molecules that regulate a multitude of cellular responses via receptor-mediated pathways, including cell...
4.
Stables M, Newson J, Ayoub S, Brown J, Hyams C, Gilroy D
Blood . 2010 Jul; 116(16):2950-9. PMID: 20606163
Inhibition of cyclooxygenase (COX)-derived prostaglandins (PGs) by nonsteroidal anti-inflammatory drugs (NSAIDs) mediates leukocyte killing of bacteria. However, the relative contribution of COX1 versus COX2 to this process, as well as...