Megan Schwarz
Overview
Explore the profile of Megan Schwarz including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
411
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Recent Articles
1.
Mzoughi S, Schwarz M, Wang X, Demircioglu D, Ulukaya G, Mohammed K, et al.
Nat Genet
. 2025 Feb;
57(2):402-412.
PMID: 39930084
Targeting cancer stem cells (CSCs) is crucial for effective cancer treatment, yet resistance mechanisms to LGR5 CSC depletion in WNT-driven colorectal cancer (CRC) remain elusive. In the present study, we...
2.
Mzoughi S, Schwarz M, Wang X, Demircioglu D, Ulukaya G, Mohammed K, et al.
bioRxiv
. 2023 Dec;
PMID: 38106050
Targeting cancer stem cells (CSCs) is crucial for effective cancer treatment . However, the molecular mechanisms underlying resistance to LGR5 CSCs depletion in colorectal cancer (CRC) remain largely elusive. Here,...
3.
Torre D, Fstkchyan Y, Ho J, Cheon Y, Patel R, DeGrace E, et al.
Mol Cell
. 2023 Nov;
83(23):4255-4271.e9.
PMID: 37995687
Endogenous retroviruses (ERVs) are remnants of ancient parasitic infections and comprise sizable portions of most genomes. Although epigenetic mechanisms silence most ERVs by generating a repressive environment that prevents their...
4.
Rialdi A, Duffy M, Scopton A, Fonseca F, Zhao J, Schwarz M, et al.
Nat Cancer
. 2023 Aug;
4(8):1157-1175.
PMID: 37537299
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths worldwide. β-Catenin (CTNNB1)-mutated HCC represents 30% of cases of the disease with no precision therapeutics available. Using chemical libraries derived...
5.
Schwarz M, Mzoughi S, Lozano-Ojalvo D, Tan A, Bertoletti A, Guccione E
Curr Res Immunol
. 2022 Sep;
3:215-221.
PMID: 36065205
As vaccine deployment improves the healthcare emergency status caused by the SARS-CoV-2 pandemic, we need reliable tools to evaluate the duration of protective immunity at a global scale. Seminal studies...
6.
Schwarz M, Torre D, Lozano-Ojalvo D, Tan A, Tabaglio T, Mzoughi S, et al.
Nat Biotechnol
. 2022 Jun;
40(11):1680-1689.
PMID: 35697804
Fast, high-throughput methods for measuring the level and duration of protective immune responses to SARS-CoV-2 are needed to anticipate the risk of breakthrough infections. Here we report the development of...
7.
Gonzalez-Perez M, Montes-Casado M, Conde P, Cervera I, Baranda J, Berges-Buxeda M, et al.
Front Immunol
. 2022 Apr;
13:845882.
PMID: 35401504
Long-term hemodialysis (HD) patients are considered vulnerable and at high-risk of developing severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) infection due to their immunocompromised condition. Since COVID-19 associated mortality...
8.
Lozano-Ojalvo D, Camara C, Lopez-Granados E, Nozal P, Del Pino-Molina L, Bravo-Gallego L, et al.
Cell Rep
. 2021 Aug;
36(8):109570.
PMID: 34390647
The rapid development of mRNA-based vaccines against the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) led to the design of accelerated vaccination schedules that have been extremely effective in naive individuals....
9.
Ho J, Di Tullio F, Schwarz M, Low D, Incarnato D, Gay F, et al.
Elife
. 2021 Jun;
10.
PMID: 34075878
High spliceosome activity is a dependency for cancer cells, making them more vulnerable to perturbation of the splicing machinery compared to normal cells. To identify splicing factors important for prostate...
10.
Guccione E, Schwarz M, Di Tullio F, Mzoughi S
Curr Opin Pharmacol
. 2021 May;
59:33-42.
PMID: 34052526
Protein arginine methylation is an abundant post-translational modification involved in the modulation of essential cellular processes ranging from transcription, post-transcriptional RNA metabolism, and propagation of signaling cascades to the regulation...