Megan C Mears
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Explore the profile of Megan C Mears including associated specialties, affiliations and a list of published articles.
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11
Citations
253
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Recent Articles
1.
Kuhn A, Outlaw V, Marcink T, Yu Z, Mears M, Cajimat M, et al.
J Virol
. 2025 Feb;
:e0215924.
PMID: 39902960
Importance: Despite the existence of vaccines for SARS-CoV-2, the constant evolution of new variants and the occurrence of breakthrough infections highlight the need for new and effective antiviral approaches. We...
2.
Mears M, Read Q, Bakre A
J Virol Methods
. 2024 Dec;
333:115103.
PMID: 39724954
Rapidly identifying and sequencing viral pathogens in poultry flocks can substantially reduce economic loss especially during disease outbreaks. Current next generation sequencing technologies require multi-step laboratory-intensive workflows to generate sequence...
3.
Mears M, Bakre A
Viruses
. 2024 Nov;
16(11).
PMID: 39599862
Post-transcriptional gene regulation mediated by microRNAs (miRNAs) relies on sequence complementarity between the miRNA seed site and the target gene transcript(s). This complementarity can completely inhibit or reduce translation into...
4.
Mears M, Olivier T, Williams-Coplin D, Espinoza E, Bakre A
Sci Rep
. 2024 Aug;
14(1):18047.
PMID: 39103419
Newcastle disease (ND), an economically important disease in poultry, is caused by virulent strains of the genetically diverse Orthoavulavirus javaense (OAVJ). Laboratories rely on quantitative real-time reverse transcription PCR (qRT-PCR)...
5.
Mears M, Ntiforo C, Sauer L, Mehta A, Levine C
Health Secur
. 2023 Dec;
22(1):58-64.
PMID: 38054936
The Federal Select Agent Program ensures the safe and secure possession, use, and transfer of biological select agents and toxins through the select agent regulations (42 CFR §73, 7 CFR...
6.
Scher G, Bente D, Mears M, Cajimat M, Schnell M
NPJ Vaccines
. 2023 May;
8(1):73.
PMID: 37210392
Crimean-Congo Hemorrhagic Fever Virus (CCHFV) is a tick-borne virus that causes severe hemorrhagic disease in humans. There is a great need for effective vaccines and therapeutics against CCHFV for humans,...
7.
Mears M, Bente D
Zoonoses (Burlingt)
. 2023 May;
2(1).
PMID: 37206318
Objective: There is no licensed vaccine available to prevent the severe tick-borne disease Crimean-Congo hemorrhagic fever (CCHF), caused by the CCHF virus (CCHFV). This study sought to show that a...
8.
Mears M, Rodriguez S, Schmitz K, Padilla A, Biswas S, Cajimat M, et al.
Antiviral Res
. 2022 Sep;
207:105401.
PMID: 36049554
Crimean-Congo hemorrhagic fever (CCHF) is a medically relevant tick-borne viral disease caused by the Bunyavirus, Crimean-Congo hemorrhagic fever virus (CCHFV). CCHFV is endemic to Asia, the Middle East, South-eastern Europe,...
9.
Outlaw V, Bovier F, Mears M, Cajimat M, Zhu Y, Lin M, et al.
mBio
. 2020 Oct;
11(5).
PMID: 33082259
The emergence of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), the etiological agent of the 2019 coronavirus disease (COVID-19), has erupted into a global pandemic that has led to...
10.
Lieberman N, Peddu V, Xie H, Shrestha L, Huang M, Mears M, et al.
PLoS Biol
. 2020 Sep;
18(9):e3000849.
PMID: 32898168
Despite limited genomic diversity, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has shown a wide range of clinical manifestations in different patient populations. The mechanisms behind these host differences are...