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Mega Obukohwo Oyovwi

Explore the profile of Mega Obukohwo Oyovwi including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Oyovwi M, Udi O, Atere A, Joseph G, Ogbutor U
Mol Biol Rep . 2025 Feb; 52(1):240. PMID: 39961877
Neurodegenerative diseases like Parkinson's and Alzheimer's are a global health challenge due to their progressive degeneration, leading to cognitive decline and motor dysfunction. Monoamine oxidase B (MAO-B) enzyme is implicated...
2.
Ajayi A, Oyovwi M, Akano O, Akanbi G, Adisa F
Cancer Cell Int . 2025 Feb; 25(1):33. PMID: 39901204
Reproductive cancers, including prostate and ovarian cancer, are highly prevalent worldwide and pose significant health challenges. The molecular underpinnings of these cancers are complex and involve dysregulation of various cellular...
3.
Oyovwi M, Ogenma U, Onyenweny A
Mol Biol Rep . 2025 Jan; 52(1):140. PMID: 39832087
This review investigates the intricate relationship between exercise, brain-derived neurotrophic factor (BDNF), neuroplasticity, and cognitive function, with a focus on implications for neuropsychiatric and neurodegenerative disorders. A systematic review was...
4.
Oyovwi M, Atere A, Chimwuba P, Joseph U
Neurotox Res . 2024 Dec; 43(1):1. PMID: 39680194
Pyrethroids, synthetic insecticides used in pest management, pose health risks, particularly neurotoxic effects, with studies linking exposure to a neurodegenerative disorder. This review examines the neurotoxic mechanisms of pyrethroids analyzing...
5.
Oyovwi M, Ugwuishi E, Udi O, Uchechukwu G
J Mol Neurosci . 2024 Nov; 74(4):107. PMID: 39514132
Mitochondria play a pivotal role in cellular metabolism, energy production, and apoptotic signaling, making mitophagy, the selective degradation of damaged mitochondria, crucial for mitochondrial health. Dysregulation of mitophagy has been...
6.
Oyovwi M, Udi O
Mol Neurobiol . 2024 Oct; 62(4):4576-4590. PMID: 39466574
Traumatic brain injury (TBI) is a major global disability and mortality cause, with the gut-brain axis playing a crucial role in its pathophysiology. Neuroinflammation, triggered by microglia and astrocytes, contributes...
7.
Ajayi A, Oyovwi M, Olatinwo G, Phillips A
Mol Biol Rep . 2024 Jul; 51(1):881. PMID: 39085654
Introduction: Epigenetics studies gene expression changes influenced by environmental and lifestyle factors, linked to health conditions like reproductive aging. Male reproductive aging causes sperm decline, conceiving difficulties, and increased genetic...
8.
Emojevwe V, Nwangwa E, Naiho A, Oyovwi M, Igiehon O, Ogunwole E, et al.
Andrologia . 2022 Jul; 54(9):e14508. PMID: 35842931
The therapeutic efficacy of N-acetylcysteine (NAC) and zinc sulphate on di-(2-ethylhexyl) phthalate (DEHP)-induced testicular oxido-nitrergic stress in rats was investigated in 36 male Wistar rats (170 ± 10 g) randomly...